Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Inositol, particularly the myo-inositol form, has been investigated for its role in supporting and treating anxiety, especially within the context of panic disorder and obsessive-compulsive disorder (OCD). Several clinical studies have explored its efficacy. For example, a double-blind, placebo-controlled study published in the American Journal of Psychiatry (1995) found that patients with panic disorder who received inositol (18g per day) experienced significantly fewer panic attacks compared to placebo. Additional research, including a 2001 study in European Neuropsychopharmacology, also suggested potential benefit for those with panic disorder and OCD. Myo-inositol appears to act on neurotransmitter pathways, particularly influencing serotonin signaling, which is implicated in anxiety regulation.

However, the body of evidence remains relatively limited, with most studies being small and of short duration. There is a lack of large-scale, long-term clinical trials, and the optimal dosing and safety profile are not fully established outside of research settings. Nonetheless, the existing data provide moderate scientific validation for the use of inositol in certain anxiety-related conditions, particularly panic disorder, justifying a rating of 3 out of 5. Inositol is generally well-tolerated, with mild gastrointestinal side effects being the most commonly reported issue. More research is needed to clarify its role in generalized anxiety disorder and other anxiety-related conditions.

More about inositol
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Other ingredients used for Anxiety

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