Evidence supporting the use of: Nitrous Oxide
For the health condition: Anxiety

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Nitrous oxide, commonly known as "laughing gas," has scientific validation for its use in the management of anxiety, particularly in medical and dental settings. Nitrous oxide is an inhaled anesthetic with anxiolytic (anxiety-reducing) properties. Upon inhalation, nitrous oxide acts rapidly on the central nervous system, producing sedation, analgesia, and euphoria, which collectively help to alleviate anxiety. Numerous clinical studies and systematic reviews have demonstrated its efficacy in reducing anxiety and discomfort during dental procedures, minor surgeries, and in pediatric patients. The anxiolytic effects are believed to be mediated through modulation of GABAergic and NMDA receptor pathways in the brain.

The use of nitrous oxide for anxiety has been standard practice in dentistry for over a century, and its safety profile is well established when administered by trained professionals. It is especially beneficial for individuals with dental phobias, children, or those who require minor surgical interventions but wish to avoid deeper sedation. Nitrous oxide is not associated with long-term anxiolytic effects and is not used for the chronic management of anxiety disorders; its use is limited to acute, procedural anxiety. The rapid onset and quick recovery profile make it a preferred choice in clinical settings.

In summary, the use of nitrous oxide to treat acute procedural anxiety is supported by strong scientific evidence and is a widely accepted medical practice.

More about Nitrous Oxide
More about Anxiety

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5-Hydroxytryptophan (5-HTP)
alpha-pinene
amino acids
ashwagandha
waterhyssop
basil
benegut perilla (proprietary)
bergamot
beta caryophyllene
bifidobacterium bifidum
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
black cumin
bupleurum falcatum
California poppy
cannabis sativa oil
chamomile
Chinese salvia root
citrus oil
clove
cordyceps
curcumin
damiana
DHA (docosahexaeonic acid)
epigallocatechin gallate (EGCG)
fennel
gardenia
ginkgo biloba
ginseng
gotu kola
greek mountain tea
green tea
guayusa
hemp oil
hops
Indian tinospora
inositol
jujube
kava root
kudzu
l-glycine
l-theanine
l-tryptophan
lactium casein decapeptide
lactobacillus brevis
lactobacillus fermentum
lactobacillus gasseri
lactobacillus helveticus
lactobacillus paracasei
lactiplantibacillus plantarum
lactobacillus reuteri
lactobacillus rhamnosus
lactobacillus salivarius
lavender
lion's mane
lithium orotate
maca
magnesium
magnolia
matcha
melatonin
mint
motherwort
muira puama
n-acetyl-cysteine (NAC)
omega-3 fatty acids
passionflower
phellodendron amurense
phosphatidylserine
phytocannabinoids
polygala root
prebiotic blend (proprietary)
pregnenolone
pyridoxal-5-phosphate (P-5-P)
reishi mushroom
relora® (proprietary)
rhizome
rhodiola
rose oil
rosemary
saffron
sage
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
sceletium
skullcap
spearmint leaf
sphaeranthus indicus
thyme
valerian root
velvet bean
vitamin B
vitamin B12
vitamin B6
vitamin C
zinc
squawvine
catnip
gastrodia
cardamom
shen-chu
mugwort
anise
tinospora cordifolia
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peony
lingzhi
lemongrass
kanna
silk tree
chrysanthemum
ganoderma
sweet flag
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menthol oil
St. John's Wort
wood betony
hypothalamus
herbal blend (proprietary)
indigo leaves
cocoa
soursop
geranium
7,8-Dihydroxyflavone
Ash
Agastache
Alpha-terpineol
Ardisia
Agrimony
Apigenin
Anamu
Albizia
Aconite
Agmatine
Agarwood
Anemone
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Asteracea
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Camellia sinensis
Centella triterpenes
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Centella asiatica
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Products containing Nitrous Oxide

We currently have no products on Vitabase that contain this ingredient.