Evidence supporting the use of: Serotonin
For the health condition: Anxiety

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Serotonin itself is not directly used as a treatment for anxiety, but the role of serotonin in anxiety disorders is well established in scientific literature. Most pharmacological treatments for anxiety—such as selective serotonin reuptake inhibitors (SSRIs)—work by increasing serotonin levels in the brain. SSRIs (like sertraline, fluoxetine, and paroxetine) are first-line medications for several anxiety disorders, including generalized anxiety disorder, panic disorder, and social anxiety disorder. The scientific rationale arises from evidence that serotonergic neurotransmission is often dysregulated in anxiety disorders. Numerous randomized controlled trials and meta-analyses have shown that SSRIs are effective in reducing anxiety symptoms, supporting the idea that enhancing serotonin availability can alleviate anxiety. However, serotonin itself cannot be administered as a supplement or drug to treat anxiety, because it does not readily cross the blood-brain barrier and is rapidly metabolized. The scientific evidence, therefore, supports the manipulation of serotonin levels via pharmacological agents, not the direct administration of serotonin. In summary, while serotonin is central to the scientific understanding and treatment of anxiety, the direct use of serotonin as an anxiolytic agent is not practiced; instead, drugs that modulate serotonergic pathways are validated and widely used.

More about Serotonin
More about Anxiety

Other ingredients used for Anxiety

5-Hydroxytryptophan (5-HTP)
alpha-pinene
amino acids
ashwagandha
waterhyssop
basil
benegut perilla (proprietary)
bergamot
beta caryophyllene
bifidobacterium bifidum
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
black cumin
bupleurum falcatum
California poppy
cannabis sativa oil
chamomile
Chinese salvia root
citrus oil
clove
cordyceps
curcumin
damiana
DHA (docosahexaeonic acid)
epigallocatechin gallate (EGCG)
fennel
gardenia
ginkgo biloba
ginseng
gotu kola
greek mountain tea
green tea
guayusa
hemp oil
hops
Indian tinospora
inositol
jujube
kava root
kudzu
l-glycine
l-theanine
l-tryptophan
lactium casein decapeptide
lactobacillus brevis
lactobacillus fermentum
lactobacillus gasseri
lactobacillus helveticus
lactobacillus paracasei
lactiplantibacillus plantarum
lactobacillus reuteri
lactobacillus rhamnosus
lactobacillus salivarius
lavender
lion's mane
lithium orotate
maca
magnesium
magnolia
matcha
melatonin
mint
motherwort
muira puama
n-acetyl-cysteine (NAC)
omega-3 fatty acids
passionflower
phellodendron amurense
phosphatidylserine
phytocannabinoids
polygala root
prebiotic blend (proprietary)
pregnenolone
pyridoxal-5-phosphate (P-5-P)
reishi mushroom
relora® (proprietary)
rhizome
rhodiola
rose oil
rosemary
saffron
sage
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
sceletium
skullcap
spearmint leaf
sphaeranthus indicus
thyme
valerian root
velvet bean
vitamin B
vitamin B12
vitamin B6
vitamin C
zinc
squawvine
catnip
gastrodia
cardamom
shen-chu
mugwort
anise
tinospora cordifolia
blackboard tree
peony
lingzhi
lemongrass
kanna
silk tree
chrysanthemum
ganoderma
sweet flag
oriental arborvitae
menthol oil
St. John's Wort
wood betony
hypothalamus
herbal blend (proprietary)
indigo leaves
cocoa
soursop
geranium
7,8-Dihydroxyflavone
Ash
Agastache
Alpha-terpineol
Ardisia
Agrimony
Apigenin
Anamu
Albizia
Aconite
Agmatine
Agarwood
Anemone
Alpha lactalbumin
Asteracea
Aniracetam
Amor seco
Betony
Black Seed
Bifidobacterium
Baikal Skullcap
Bifidobacterium adolescentis
Balsam
Bayleaf
Bacopin
Baicalein
Brahmi
Bacopa
Bee products
Bombax
Bacteria
Bifidobacteria
Bupleurum
bacoside
Baicalin
Borneol
Camellia sinensis
Centella triterpenes
Caryophyllene
Common Monkey Flower
Cinnamomum
Clary sage
Capillary Artemisia
Citron
Chinese Raisintree
Cymbopogon Martini
Calea zacatechichi
Centella asiatica
Capitate Valerian
Curcuma
Catuaba
Cowslip
Cannabidiol
Calamus
Clostridium butyricum
Convolvulus prostratus
Convolvulus Pluricaulis
Clerodendrum indicum
Canscora
Cannabigerol
Dodeca-2E, 4E-Dienoic Acid Isobutylamide
Dragonhead
Erythrina
Essential Oil Blend
Eugenol
Fatty acids
Glycine
jasmine
Lotus
Mimosa
Poppy
Rose
Spikenard
Sandalwood
Sweet Orange alcohol
Vervain
yohimbine

Other health conditions supported by Serotonin

Anxiety
Anxiety Disorders
Depression
Mood Swings
Seasonal Affective Disorder

Products containing Serotonin

We currently have no products on Vitabase that contain this ingredient.