Evidence supporting the use of: Sophora
For the health condition: Anxiety

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Sophora is a genus of plants used in traditional medicine systems, particularly in East Asia. Species such as Sophora flavescens ("Ku Shen") have a long history of use in Traditional Chinese Medicine (TCM) for a range of indications, including as a general tonic and to "clear heat," but anxiety is not a primary or classical indication. There are scattered traditional references to its calming or sedative effects, which may be related to its use in formulas intended to address agitation or restlessness, often in the context of fever or other disorders. However, these references are not widespread or central to its ethnobotanical use, and there is no strong tradition of using Sophora species specifically for anxiety.

From a scientific perspective, there are few studies directly investigating Sophora species or their isolated compounds for anxiolytic (anxiety-reducing) effects. Most available research focuses on antimicrobial, anti-inflammatory, or anticancer activities. Only preliminary animal studies suggest that certain alkaloids found in Sophora, such as matrine and oxymatrine, may have central nervous system effects, but anxiolytic activity has not been robustly demonstrated or widely studied. As such, evidence for the use of Sophora to support or treat anxiety is primarily based on limited traditional use and lacks strong scientific validation.

More about Sophora
More about Anxiety

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Products containing Sophora

We currently have no products on Vitabase that contain this ingredient.