Evidence supporting the use of: Bacoside
For the health condition: Anxiety Disorders

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Bacoside is the primary active constituent of Bacopa monnieri, a traditional Ayurvedic herb also known as Brahmi. While Bacopa has a long history of use in traditional medicine for cognitive enhancement and stress adaptation, its specific effects on anxiety disorders have been increasingly investigated in recent years. Several preclinical studies (animal models) have demonstrated that bacosides have anxiolytic (anxiety-reducing) effects, likely mediated through modulation of neurotransmitter systems such as serotonin and GABA, and through antioxidant mechanisms that protect neural tissue from stress-induced damage.

Human evidence for Bacopa’s anxiolytic effects is limited but growing. A handful of randomized controlled trials (RCTs) have evaluated standardized Bacopa extracts and reported reductions in self-reported anxiety and improvements in mood, though most studies were conducted in healthy adults or those with mild cognitive impairment rather than individuals diagnosed with clinical anxiety disorders. Meta-analyses suggest small but statistically significant decreases in anxiety scores with Bacopa supplementation; however, methodological limitations (small sample sizes, varying dosages and extract standardizations, lack of clinical anxiety populations) prevent strong conclusions.

Overall, while there is preliminary scientific validation for bacoside-containing Bacopa extracts as supportive agents for anxiety reduction, the evidence base remains modest (rated 2/5) and further well-designed clinical trials are needed to confirm efficacy in anxiety disorders specifically.

More about bacoside
More about Anxiety Disorders

Other ingredients used for Anxiety Disorders

5-Hydroxytryptophan (5-HTP)
7,8-Dihydroxyflavone
Aconite
Albizia
amino acids
apigenin
ashwagandha
Bacopa
Bacopin
bacoside
Baikal Skullcap
beta caryophyllene
Bifidobacterium adolescentis
Bifidobacterium infantis
Bifidobacterium longum
brahmi
cannabidiol
Cannabis sativa oil
Capitate Valerian
catnip
Centella asiatica
chamomile
Clary sage
cocoa
Convolvulus pluricaulis
Convolvulus prostratus
cowslip
curcumin
Cymbopogon martini
essential oil blend
gastrodin
Gelsemium
ginkgo biloba
Ginkgoside
ginseng
gotu kola
green tea
Griffonia simplicifolia
hemp
hemp oil
herbal blend (proprietary)
hericium mushroom
Honokiol
hyperforin
Hypericum
inositol
jujubosides
kava
kavalactones
Kefir
L-glycine
L-taurine
L-theanine
L-tryptophan
lactium casein decapeptide
Lactobacillus
Lactobacillus casei
Lactobacillus paracasei
Lactobacillus rhamnosus
Lactococcus rhamnosus
Large-leaved linden
Lavandin
lavender
lemon balm
linalool
linden
lion's mane
lithium orotate
magnesium
magnolia
magnolol
Matcha
Melatonin
Mesembrine
Mimulus
Monoterpenes
Motherwort
Muira puama
Mulungu
N-acetyl-cysteine (NAC)
omega-3 fatty acids
passionflower
Passionfruit
phosphatidylserine
phytocannabinoids
Polygala
polygala root
prebiotic blend (proprietary)
pregnenolone
probiotics
Pulsatilla
Purple Monkeyflower
pyridoxal-5-phosphate (P-5-P)
reishi mushroom
relora® (proprietary)
Rhodiola
rosavins
rosmarinic acid
Safranal
SAMe (S-adenosyl-L-methionine disulfate p-toluensulfate)
Sandalwood
sceletium
Scleranthus annus
Shankhpushpi
shen-chu
skullcap
Spikenard
St. John's Wort
star of Bethlehem
Tea
Terpenoids
Tetrahydropalmatine
Trichilia catigua
Valerenic acid
Valerian root
velvet bean
Vervain
vitamin B
vitamin B12
vitamin B6
Vitexin
Waterhyssop
Wogonin
Yohimbine
Zinc

Products containing bacoside

We currently have no products on Vitabase that contain this ingredient.