Evidence supporting the use of: Blue Vervain
For the health condition: Anxiety Disorders
Synopsis
Source of validity: Traditional
Rating (out of 5): 1
Blue Vervain (Verbena hastata) has a long history of use in traditional herbal medicine, particularly within Western herbalism and Native American practices, as a remedy for anxiety, nervousness, and related conditions. Its reputation as a calming herb, or “nervine,” is rooted primarily in traditional practice rather than robust scientific studies. Traditional herbalists often prepared Blue Vervain as a tea, tincture, or infusion to promote relaxation and ease symptoms of anxiety or mental stress.
Despite its historical use, scientific validation is limited. Most modern clinical studies on Blue Vervain are lacking, and there is insufficient high-quality evidence from randomized controlled trials to confirm its efficacy in treating anxiety disorders. A handful of animal studies suggest some sedative or anxiolytic effects, possibly related to certain phytochemicals such as flavonoids or glycosides, but these findings have not been replicated or confirmed in humans. As such, mainstream medical and psychiatric guidelines do not recognize Blue Vervain as a proven treatment for anxiety.
In summary, while Blue Vervain continues to be used by some herbalists for anxiety, its justification comes almost entirely from traditional use rather than scientific validation. Its evidence rating remains low due to the absence of rigorous clinical research.
Other ingredients used for Anxiety Disorders
5-Hydroxytryptophan (5-HTP)amino acids
ashwagandha
waterhyssop
beta caryophyllene
bifidobacterium infantis
bifidobacterium longum
cannabis sativa oil
chamomile
citrus oil
curcumin
ginkgo biloba
ginseng
gotu kola
green tea
hemp oil
inositol
kava root
l-glycine
l-taurine
l-theanine
l-tryptophan
lactium casein decapeptide
lactobacillus casei
lactobacillus paracasei
lactobacillus rhamnosus
lavender
lion's mane
lithium orotate
magnesium
magnolia
matcha
melatonin
motherwort
muira puama
n-acetyl-cysteine (NAC)
omega-3 fatty acids
passionflower
phosphatidylserine
phytocannabinoids
polygala root
prebiotic blend (proprietary)
pregnenolone
pyridoxal-5-phosphate (P-5-P)
reishi mushroom
relora® (proprietary)
rhodiola
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
sceletium
skullcap
valerian root
velvet bean
vitamin B
vitamin B12
vitamin B6
zinc
catnip
shen-chu
St. John's Wort
herbal blend (proprietary)
cocoa
7,8-Dihydroxyflavone
Apigenin
Albizia
Aconite
Baikal Skullcap
Bifidobacterium adolescentis
Bacopin
Brahmi
Bacopa
bacoside
Clary sage
Cymbopogon Martini
Centella asiatica
Capitate Valerian
Cowslip
Cannabidiol
Convolvulus prostratus
Convolvulus Pluricaulis
Essential Oil Blend
Spikenard
Sandalwood
Vervain
yohimbine
Other health conditions supported by Blue Vervain
AnxietyAnxiety Disorders
Appetite (deficient)
Backache
Bites and Stings
Bruises (healing)
Colds (general)
Cramps and Spasms
Depression
Digestion (poor)
Edema
Emotional Sensitivity
Fatigue
Fever
Headache (general)
Indigestion
Inflammation
Insomnia
Irritability
Menstrual Irregularity
Muscle Tone (lack of)
Nervous Exhaustion
Nervousness
Pain (general remedies for)
Post Traumatic Stress Disorder
Stress
Worry
Wounds and Sores