Evidence supporting the use of: Centella asiatica
For the health condition: Anxiety Disorders

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Centella asiatica, also known as gotu kola, has a long history of use in traditional medicine systems such as Ayurveda and Traditional Chinese Medicine (TCM), where it is believed to promote mental calmness and alleviate symptoms associated with anxiety and stress. Traditionally, it has been used as a tonic for the nervous system and to improve cognitive function, which includes potential anxiolytic (anxiety-reducing) effects. Scientific studies investigating the anxiolytic properties of Centella asiatica are limited but suggest some promise. Small-scale animal studies have indicated that extracts of Centella asiatica may reduce anxiety-like behaviors, possibly by modulating neurotransmitter activity or influencing the GABAergic system. Human evidence is more limited; a few small clinical trials and pilot studies report reduced anxiety symptoms following supplementation, but methodological limitations and small sample sizes prevent definitive conclusions. A 2013 review (Wijeweera et al., 2006, and others) notes that while preliminary evidence is encouraging, more rigorous, large-scale human clinical trials are needed to confirm efficacy and clarify mechanisms. Thus, while traditional use is well-documented and there is some emerging scientific support, the current evidence base is not strong or comprehensive enough to fully endorse Centella asiatica as a treatment for anxiety disorders.

More about Centella asiatica
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Other ingredients used for Anxiety Disorders

5-Hydroxytryptophan (5-HTP)
7,8-Dihydroxyflavone
Aconite
Albizia
amino acids
apigenin
ashwagandha
Bacopa
Bacopin
bacoside
Baikal Skullcap
beta caryophyllene
Bifidobacterium adolescentis
Bifidobacterium infantis
Bifidobacterium longum
brahmi
cannabidiol
Cannabis sativa oil
Capitate Valerian
catnip
Centella asiatica
chamomile
Clary sage
cocoa
Convolvulus pluricaulis
Convolvulus prostratus
cowslip
curcumin
Cymbopogon martini
essential oil blend
gastrodin
Gelsemium
ginkgo biloba
Ginkgoside
ginseng
gotu kola
green tea
Griffonia simplicifolia
hemp
hemp oil
herbal blend (proprietary)
hericium mushroom
Honokiol
hyperforin
Hypericum
inositol
jujubosides
kava
kavalactones
Kefir
L-glycine
L-taurine
L-theanine
L-tryptophan
lactium casein decapeptide
Lactobacillus
Lactobacillus casei
Lactobacillus paracasei
Lactobacillus rhamnosus
Lactococcus rhamnosus
Large-leaved linden
Lavandin
lavender
lemon balm
linalool
linden
lion's mane
lithium orotate
magnesium
magnolia
magnolol
Matcha
Melatonin
Mesembrine
Mimulus
Monoterpenes
Motherwort
Muira puama
Mulungu
N-acetyl-cysteine (NAC)
omega-3 fatty acids
passionflower
Passionfruit
phosphatidylserine
phytocannabinoids
Polygala
polygala root
prebiotic blend (proprietary)
pregnenolone
probiotics
Pulsatilla
Purple Monkeyflower
pyridoxal-5-phosphate (P-5-P)
reishi mushroom
relora® (proprietary)
Rhodiola
rosavins
rosmarinic acid
Safranal
SAMe (S-adenosyl-L-methionine disulfate p-toluensulfate)
Sandalwood
sceletium
Scleranthus annus
Shankhpushpi
shen-chu
skullcap
Spikenard
St. John's Wort
star of Bethlehem
Tea
Terpenoids
Tetrahydropalmatine
Trichilia catigua
Valerenic acid
Valerian root
velvet bean
Vervain
vitamin B
vitamin B12
vitamin B6
Vitexin
Waterhyssop
Wogonin
Yohimbine
Zinc

Products containing Centella asiatica

We currently have no products on Vitabase that contain this ingredient.