Evidence supporting the use of: Flavanoid (mixture)
For the health condition: Anxiety Disorders

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Flavonoids are a diverse group of plant-derived polyphenolic compounds found in foods such as fruits, vegetables, tea, and wine. There is emerging scientific evidence suggesting that certain flavonoids may exert anxiolytic (anxiety-reducing) effects, primarily through modulation of neurotransmitter systems, antioxidant activity, and anti-inflammatory effects. Preclinical studies, particularly in rodent models, have demonstrated that flavonoids such as quercetin, apigenin, luteolin, and kaempferol can reduce anxiety-like behaviors. Mechanistic studies indicate that these effects may be mediated via the GABAergic system, serotonergic modulation, and reduction of oxidative stress. A small number of early-phase clinical trials have explored the impact of flavonoid-rich extracts (e.g., from passionflower or chamomile) on anxiety symptoms in humans, showing some promise but with mixed results. However, these studies often use extracts containing multiple bioactive ingredients, making it difficult to attribute effects specifically to flavonoids. There is currently insufficient high-quality, large-scale clinical evidence to support the widespread use of flavonoid mixtures as anxiolytic agents in humans. Overall, while the mechanistic basis and animal data are encouraging, clinical validation remains limited, and more rigorous trials are needed to fully establish efficacy and safety.

More about Flavanoid (mixture)
More about Anxiety Disorders

Other ingredients used for Anxiety Disorders

5-Hydroxytryptophan (5-HTP)
amino acids
ashwagandha
waterhyssop
beta caryophyllene
bifidobacterium infantis
bifidobacterium longum
cannabis sativa oil
chamomile
citrus oil
curcumin
ginkgo biloba
ginseng
gotu kola
green tea
hemp oil
inositol
kava
L-glycine
L-taurine
L-theanine
L-tryptophan
lactium casein decapeptide
lactobacillus casei
lactobacillus paracasei
lactobacillus rhamnosus
lavender
lion's mane
lithium orotate
magnesium
magnolia
matcha
melatonin
motherwort
muira puama
n-acetyl-cysteine (NAC)
omega-3 fatty acids
passionflower
phosphatidylserine
phytocannabinoids
polygala root
prebiotic blend (proprietary)
pregnenolone
pyridoxal-5-phosphate (P-5-P)
reishi mushroom
relora® (proprietary)
rhodiola
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
sceletium
skullcap
valerian root
velvet bean
vitamin B
vitamin B12
vitamin B6
zinc
catnip
shen-chu
St. John's Wort
herbal blend (proprietary)
cocoa
star of Bethlehem
7,8-Dihydroxyflavone
Apigenin
Albizia
Aconite
Baikal Skullcap
Bifidobacterium adolescentis
Bacopin
Brahmi
Bacopa
bacoside
Clary sage
Cymbopogon Martini
Centella asiatica
Capitate Valerian
Cowslip
Cannabidiol
Convolvulus prostratus
Convolvulus Pluricaulis
Essential Oil Blend
Gelsemium
Griffonia simplicifolia
Ginkgoside
Gastrodin
Honokiol
Hypericum
hyperforin
Hericium mushroom
Hemp
Jujubosides
Kavalactones
Kefir
lemon balm
Linden
Lactococcus rhamnosus
Lavandin
Large-Leaved Linden
Lactobacillus
Linalool
Mimulus
Monoterpenes
Magnolol
Mulungu
Mesembrine
Pulsatilla
Probiotics
Passionfruit
Polygala
Purple Monkeyflower
Rosavins
Rosmarinic Acid
Spikenard
Scleranthus annus
Shankhpushpi
Sandalwood
Saffranal
Terpenoids
Tea
Trichilia catigua
Tetrahydropalmatine
Valerenic acid
Vervain
Vitexin
Wogonin
yohimbine

Products containing Flavanoid (mixture)

We currently have no products on Vitabase that contain this ingredient.