Evidence supporting the use of: Ginkgo flavones
For the health condition: Anxiety Disorders

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Ginkgo biloba, which contains flavones and other flavonoids, has a long history of use in traditional medicine, particularly in China, for various cognitive and mood-related conditions. Its use for anxiety is primarily justified by tradition rather than robust scientific evidence. Some small clinical trials and animal studies have explored Ginkgo’s potential anxiolytic (anxiety-reducing) effects. These studies suggest that Ginkgo extracts may influence neurotransmitter systems, such as serotonin and dopamine, which are implicated in anxiety disorders. However, the evidence is inconsistent and often limited by small sample sizes, methodological flaws, or lack of replication. A few studies have noted modest improvements in anxiety symptoms, especially in elderly patients or those with cognitive impairment, but these findings have not been widely replicated or confirmed in large, well-designed clinical trials. Major scientific reviews and meta-analyses generally conclude that there is insufficient evidence to support the use of Ginkgo flavones for treating anxiety disorders. As such, while Ginkgo’s use for anxiety is rooted in tradition and there is some preliminary research, there is not enough high-quality scientific validation to recommend it as a primary treatment for anxiety disorders.

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