Evidence supporting the use of: Hericium mushroom
For the health condition: Anxiety Disorders
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Hericium mushroom (commonly known as Lion's Mane, Hericium erinaceus) has been investigated in several preclinical and limited clinical studies for its potential effects on mental health, including anxiety disorders. Scientific interest in Lion's Mane is due to its content of bioactive compounds such as hericenones and erinacines, which may stimulate nerve growth factor (NGF) synthesis and modulate neuroinflammation.
A small number of human studies have explored Lion's Mane's anxiolytic properties. Notably, a double-blind, placebo-controlled pilot study in 2010 (Nagano et al.) involving menopausal women reported reduced scores for anxiety and irritability after four weeks of Lion's Mane supplementation. Animal studies have also shown decreased anxiety-like behaviors in rodents, possibly linked to neuroprotective and anti-inflammatory mechanisms.
However, the current body of evidence is limited by small sample sizes, short durations, and a lack of studies specifically targeting clinical anxiety disorders. Most research to date is preliminary, and there is insufficient high-quality clinical data to firmly establish Lion's Mane as an effective treatment for anxiety disorders.
In summary, while there is scientific interest and some early evidence suggesting a potential anxiolytic effect of Hericium mushroom, the quality and quantity of evidence are currently low. Larger, well-designed clinical trials are needed to confirm efficacy and safety for anxiety disorders.
Other ingredients used for Anxiety Disorders
5-Hydroxytryptophan (5-HTP)7,8-Dihydroxyflavone
Aconite
Albizia
amino acids
apigenin
ashwagandha
Bacopa
Bacopin
bacoside
Baikal Skullcap
beta caryophyllene
Bifidobacterium adolescentis
Bifidobacterium infantis
Bifidobacterium longum
brahmi
cannabidiol
Cannabis sativa oil
Capitate Valerian
catnip
Centella asiatica
chamomile
Clary sage
cocoa
Convolvulus pluricaulis
Convolvulus prostratus
cowslip
curcumin
Cymbopogon martini
essential oil blend
gastrodin
Gelsemium
ginkgo biloba
Ginkgoside
ginseng
gotu kola
green tea
Griffonia simplicifolia
hemp
hemp oil
herbal blend (proprietary)
hericium mushroom
Honokiol
hyperforin
Hypericum
inositol
jujubosides
kava
kavalactones
Kefir
L-glycine
L-taurine
L-theanine
L-tryptophan
lactium casein decapeptide
Lactobacillus
Lactobacillus casei
Lactobacillus paracasei
Lactobacillus rhamnosus
Lactococcus rhamnosus
Large-leaved linden
Lavandin
lavender
lemon balm
linalool
linden
lion's mane
lithium orotate
magnesium
magnolia
magnolol
Matcha
Melatonin
Mesembrine
Mimulus
Monoterpenes
Motherwort
Muira puama
Mulungu
N-acetyl-cysteine (NAC)
omega-3 fatty acids
passionflower
Passionfruit
phosphatidylserine
phytocannabinoids
Polygala
polygala root
prebiotic blend (proprietary)
pregnenolone
probiotics
Pulsatilla
Purple Monkeyflower
pyridoxal-5-phosphate (P-5-P)
reishi mushroom
relora® (proprietary)
Rhodiola
rosavins
rosmarinic acid
Safranal
SAMe (S-adenosyl-L-methionine disulfate p-toluensulfate)
Sandalwood
sceletium
Scleranthus annus
Shankhpushpi
shen-chu
skullcap
Spikenard
St. John's Wort
star of Bethlehem
Tea
Terpenoids
Tetrahydropalmatine
Trichilia catigua
Valerenic acid
Valerian root
velvet bean
Vervain
vitamin B
vitamin B12
vitamin B6
Vitexin
Waterhyssop
Wogonin
Yohimbine
Zinc
Other health conditions supported by hericium mushroom
Alzheimer's DiseaseAnxiety
Anxiety Disorders
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Chemotherapy (reducing side effects)
Colitis
Concentration (poor)
Depression
Diabetes
Digestion (poor)
Fatigue
Gastritis
Inflammation
Memory and Brain Function
Nerve Damage
Neuralgia and Neuritis
Parkinson's Disease
Peripheral Neuropathy
Stress
Ulcers
Wounds and Sores
