Relationship: Anxiety Disorders and inositol

Evidence supporting the use of: Inositol
For the health condition: Anxiety Disorders

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Inositol, particularly the myo-inositol isomer, has been investigated as a potential treatment for anxiety disorders, including panic disorder and obsessive-compulsive disorder (OCD). The scientific support for its use is modest but present. Several small randomized controlled trials from the late 1990s and early 2000s found that high-dose inositol (usually 12-18 grams per day) was more effective than placebo and in some cases comparable to selective serotonin reuptake inhibitors (SSRIs) in reducing symptoms of panic disorder and OCD. For example, a double-blind, controlled study by Benjamin Levine et al. (1995) showed that inositol significantly reduced the frequency and severity of panic attacks compared to placebo. Another study (Fux et al., 1996) observed beneficial effects in OCD symptoms. The proposed mechanism involves inositol's role as a precursor in the phosphatidylinositol signaling pathway, which is implicated in neurotransmitter systems (such as serotonin and dopamine) thought to underlie anxiety and mood regulation. However, most of these studies are small, short-term, and not widely replicated, with limited data on long-term efficacy and safety. Major clinical guidelines do not currently endorse inositol as a first-line treatment for anxiety disorders, but some practitioners may use it as an adjunct or alternative, especially for patients who do not tolerate standard medications. In summary, while there is some scientific evidence supporting inositol for anxiety, the overall quality and quantity of evidence are limited, justifying a moderate evidence rating.

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Other ingredients used for Anxiety Disorders

5-Hydroxytryptophan (5-HTP)
amino acids
ashwagandha
waterhyssop
beta caryophyllene
bifidobacterium infantis
bifidobacterium longum
cannabis sativa oil
chamomile
citrus oil
curcumin
ginkgo biloba
ginseng
gotu kola
green tea
hemp oil
inositol
kava root
l-glycine
l-taurine
l-theanine
l-tryptophan
lactium casein decapeptide
lactobacillus casei
lactobacillus paracasei
lactobacillus rhamnosus
lavender
lion's mane
lithium orotate
magnesium
magnolia
matcha
melatonin
motherwort
muira puama
n-acetyl-cysteine (NAC)
omega-3 fatty acids
passionflower
phosphatidylserine
phytocannabinoids
polygala root
prebiotic blend (proprietary)
pregnenolone
pyridoxal-5-phosphate (P-5-P)
reishi mushroom
relora® (proprietary)
rhodiola
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
sceletium
skullcap
valerian root
velvet bean
vitamin B
vitamin B12
vitamin B6
zinc
catnip
shen-chu
St. John's Wort
herbal blend (proprietary)
cocoa
7,8-Dihydroxyflavone
Apigenin
Albizia
Aconite
Baikal Skullcap
Bifidobacterium adolescentis
Bacopin
Brahmi
Bacopa
bacoside
Clary sage
Cymbopogon Martini
Centella asiatica
Capitate Valerian
Cowslip
Cannabidiol
Convolvulus prostratus
Convolvulus Pluricaulis
Essential Oil Blend
Gelsemium
Griffonia simplicifolia
Ginkgoside
Gastrodin
Spikenard
Sandalwood
Vervain
yohimbine

Other health conditions supported by inositol

Anxiety
Anxiety Disorders
Bipolar Mood Disorder
Bulimia
Depression
Diabetes
Memory and Brain Function
Obsessive Compulsive Disorder
PMS (general)

Products containing inositol

Health Concerns

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Evidence supporting the use of: Inositol
For the health condition: Anxiety Disorders

Table of Contents

Synopsis

Other ingredients used for Anxiety Disorders

Other health conditions supported by inositol

Products containing inositol

Health Concerns

Brands

Evidence supporting the use of: InositolFor the health condition: Anxiety Disorders

Table of Contents

Synopsis

Other ingredients used for Anxiety Disorders

Other health conditions supported by inositol

Products containing inositol

Evidence supporting the use of: Inositol
For the health condition: Anxiety Disorders