Evidence supporting the use of: Kava kava
For the health condition: Anxiety Disorders

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Kava kava (Piper methysticum) has a long history of traditional use in the South Pacific as a ceremonial beverage and for its calming effects. Its use for anxiety disorders, however, is supported by some scientific evidence. Several randomized controlled trials and meta-analyses have investigated the efficacy of kava extract in treating symptoms of anxiety. A 2011 Cochrane review concluded that kava extract appears to be more effective than placebo in the short-term treatment of anxiety, with a moderate effect size, although concerns about study quality and potential for publication bias were noted. The active compounds, termed kavalactones, are thought to modulate GABA activity in the central nervous system, contributing to kava’s anxiolytic properties without strong sedative effects. However, there are important safety concerns. Reports of hepatotoxicity led to regulatory restrictions or bans in several countries, although the exact risk and mechanism remain debated and may be related to extraction methods or quality control issues. Current clinical guidelines generally do not recommend kava as a first-line treatment for anxiety due to these safety concerns and the availability of better-studied alternatives. In summary, while there is scientific evidence supporting kava’s efficacy for anxiety, the overall quality of the evidence is moderate, and safety concerns limit its therapeutic use.

More about Kava kava
More about Anxiety Disorders

Other health conditions supported by Kava kava

Anxiety
Anxiety Disorders
Insomnia
Stress

Products containing Kava kava

We currently have no products on Vitabase that contain this ingredient.