Evidence supporting the use of: Lactobacillus
For the health condition: Anxiety Disorders

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactobacillus, a genus of probiotic bacteria, has been investigated for its potential effects on anxiety disorders through the gut-brain axis. Preclinical studies in animals have shown that certain strains of Lactobacillus can influence neurochemical pathways, reduce stress-induced behaviors, and modulate inflammatory responses. Some small human clinical trials and pilot studies have also reported modest reductions in self-reported anxiety symptoms after supplementation with specific Lactobacillus strains, such as Lactobacillus rhamnosus and Lactobacillus helveticus, often in combination with other probiotics. These effects are hypothesized to be mediated by alterations in gut microbiota composition, immune modulation, and changes in neurotransmitter levels like GABA.

However, the scientific evidence remains limited and mixed. Most studies to date are small, short-term, or lack rigorous controls. Meta-analyses and systematic reviews generally conclude that while there is some promise, the overall quality of evidence is low, and results are not consistently significant. No major clinical guidelines currently endorse Lactobacillus as an established treatment for anxiety disorders. Thus, while there is early scientific investigation supporting a possible benefit, the evidence is insufficient to justify widespread clinical use at this time.

More about Lactobacillus
More about Anxiety Disorders

Other ingredients used for Anxiety Disorders

5-Hydroxytryptophan (5-HTP)
7,8-Dihydroxyflavone
Aconite
Albizia
amino acids
apigenin
ashwagandha
Bacopa
Bacopin
bacoside
Baikal Skullcap
beta caryophyllene
Bifidobacterium adolescentis
Bifidobacterium infantis
Bifidobacterium longum
brahmi
cannabidiol
Cannabis sativa oil
Capitate Valerian
catnip
Centella asiatica
chamomile
Clary sage
cocoa
Convolvulus pluricaulis
Convolvulus prostratus
cowslip
curcumin
Cymbopogon martini
essential oil blend
gastrodin
Gelsemium
ginkgo biloba
Ginkgoside
ginseng
gotu kola
green tea
Griffonia simplicifolia
hemp
hemp oil
herbal blend (proprietary)
hericium mushroom
Honokiol
hyperforin
Hypericum
inositol
jujubosides
kava
kavalactones
Kefir
L-glycine
L-taurine
L-theanine
L-tryptophan
lactium casein decapeptide
Lactobacillus
Lactobacillus casei
Lactobacillus paracasei
Lactobacillus rhamnosus
Lactococcus rhamnosus
Large-leaved linden
Lavandin
lavender
lemon balm
linalool
linden
lion's mane
lithium orotate
magnesium
magnolia
magnolol
Matcha
Melatonin
Mesembrine
Mimulus
Monoterpenes
Motherwort
Muira puama
Mulungu
N-acetyl-cysteine (NAC)
omega-3 fatty acids
passionflower
Passionfruit
phosphatidylserine
phytocannabinoids
Polygala
polygala root
prebiotic blend (proprietary)
pregnenolone
probiotics
Pulsatilla
Purple Monkeyflower
pyridoxal-5-phosphate (P-5-P)
reishi mushroom
relora® (proprietary)
Rhodiola
rosavins
rosmarinic acid
Safranal
SAMe (S-adenosyl-L-methionine disulfate p-toluensulfate)
Sandalwood
sceletium
Scleranthus annus
Shankhpushpi
shen-chu
skullcap
Spikenard
St. John's Wort
star of Bethlehem
Tea
Terpenoids
Tetrahydropalmatine
Trichilia catigua
Valerenic acid
Valerian root
velvet bean
Vervain
vitamin B
vitamin B12
vitamin B6
Vitexin
Waterhyssop
Wogonin
Yohimbine
Zinc

Products containing Lactobacillus

We currently have no products on Vitabase that contain this ingredient.