Evidence supporting the use of: Lactobacillus paracasei
For the health condition: Anxiety Disorders

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactobacillus paracasei is a probiotic bacterium commonly found in the human gut and in fermented foods. Its use for supporting or treating anxiety disorders is primarily driven by recent scientific interest in the "gut-brain axis," the bidirectional communication between the gastrointestinal tract and the central nervous system. Several preclinical (animal) studies and a limited number of small human trials have investigated the potential of L. paracasei and other probiotics to modulate mood, stress response, and anxiety-like behaviors. Some of these studies report that supplementation with L. paracasei can reduce markers of stress and anxiety, possibly by influencing gut microbiota composition, reducing inflammation, and modulating neurotransmitter levels such as GABA and serotonin. For example, a few randomized controlled trials have shown improvements in self-reported anxiety symptoms in healthy adults and individuals with mild anxiety using multi-strain probiotic supplements containing L. paracasei. However, the overall quality of evidence is low to moderate due to small sample sizes, short duration, and the frequent use of combination products rather than isolated L. paracasei. There is insufficient evidence to recommend L. paracasei as a stand-alone treatment for clinically diagnosed anxiety disorders. More robust, large-scale clinical trials are needed to confirm its efficacy and understand the underlying mechanisms. Thus, while scientific interest is growing, the current evidence base is preliminary and limited.

More about Lactobacillus paracasei
More about Anxiety Disorders

Other ingredients used for Anxiety Disorders

5-Hydroxytryptophan (5-HTP)
7,8-Dihydroxyflavone
Aconite
Albizia
amino acids
apigenin
ashwagandha
Bacopa
Bacopin
bacoside
Baikal Skullcap
beta caryophyllene
Bifidobacterium adolescentis
Bifidobacterium infantis
Bifidobacterium longum
brahmi
cannabidiol
Cannabis sativa oil
Capitate Valerian
catnip
Centella asiatica
chamomile
Clary sage
cocoa
Convolvulus pluricaulis
Convolvulus prostratus
cowslip
curcumin
Cymbopogon martini
essential oil blend
gastrodin
Gelsemium
ginkgo biloba
Ginkgoside
ginseng
gotu kola
green tea
Griffonia simplicifolia
hemp
hemp oil
herbal blend (proprietary)
hericium mushroom
Honokiol
hyperforin
Hypericum
inositol
jujubosides
kava
kavalactones
Kefir
L-glycine
L-taurine
L-theanine
L-tryptophan
lactium casein decapeptide
Lactobacillus
Lactobacillus casei
Lactobacillus paracasei
Lactobacillus rhamnosus
Lactococcus rhamnosus
Large-leaved linden
Lavandin
lavender
lemon balm
linalool
linden
lion's mane
lithium orotate
magnesium
magnolia
magnolol
Matcha
Melatonin
Mesembrine
Mimulus
Monoterpenes
Motherwort
Muira puama
Mulungu
N-acetyl-cysteine (NAC)
omega-3 fatty acids
passionflower
Passionfruit
phosphatidylserine
phytocannabinoids
Polygala
polygala root
prebiotic blend (proprietary)
pregnenolone
probiotics
Pulsatilla
Purple Monkeyflower
pyridoxal-5-phosphate (P-5-P)
reishi mushroom
relora® (proprietary)
Rhodiola
rosavins
rosmarinic acid
Safranal
SAMe (S-adenosyl-L-methionine disulfate p-toluensulfate)
Sandalwood
sceletium
Scleranthus annus
Shankhpushpi
shen-chu
skullcap
Spikenard
St. John's Wort
star of Bethlehem
Tea
Terpenoids
Tetrahydropalmatine
Trichilia catigua
Valerenic acid
Valerian root
velvet bean
Vervain
vitamin B
vitamin B12
vitamin B6
Vitexin
Waterhyssop
Wogonin
Yohimbine
Zinc