Evidence supporting the use of: Linalool
For the health condition: Anxiety Disorders
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Linalool is a naturally occurring terpene alcohol found in many essential oils, including lavender and coriander. Its use to support or treat anxiety disorders is primarily supported by scientific evidence from preclinical (animal) studies and some human clinical trials, though the evidence is not yet robust or fully conclusive. Research indicates that linalool exerts anxiolytic (anxiety-reducing) effects, likely through modulation of the GABAergic system—the same neurotransmitter system targeted by many conventional anxiolytics. Animal studies consistently show that inhalation or administration of linalool reduces anxiety-like behaviors. Some small human studies and clinical trials, particularly with lavender oil preparations standardized for linalool content, report reductions in subjective anxiety and physiological markers such as heart rate and blood pressure.
However, large-scale, high-quality randomized controlled trials in humans are limited, and most of the evidence is derived from studies on essential oils containing linalool rather than the isolated compound itself. While the findings are promising and suggest a scientific basis for linalool’s anxiolytic effects, more rigorous human research is necessary to confirm efficacy, optimal dosing, and safety. Thus, the use of linalool for anxiety is classified as "scientific" with a moderate evidence rating of 3 out of 5.
Other ingredients used for Anxiety Disorders
5-Hydroxytryptophan (5-HTP)7,8-Dihydroxyflavone
Aconite
Albizia
amino acids
apigenin
ashwagandha
Bacopa
Bacopin
bacoside
Baikal Skullcap
beta caryophyllene
Bifidobacterium adolescentis
Bifidobacterium infantis
Bifidobacterium longum
brahmi
cannabidiol
Cannabis sativa oil
Capitate Valerian
catnip
Centella asiatica
chamomile
Clary sage
cocoa
Convolvulus pluricaulis
Convolvulus prostratus
cowslip
curcumin
Cymbopogon martini
essential oil blend
gastrodin
Gelsemium
ginkgo biloba
Ginkgoside
ginseng
gotu kola
green tea
Griffonia simplicifolia
hemp
hemp oil
herbal blend (proprietary)
hericium mushroom
Honokiol
hyperforin
Hypericum
inositol
jujubosides
kava
kavalactones
Kefir
L-glycine
L-taurine
L-theanine
L-tryptophan
lactium casein decapeptide
Lactobacillus
Lactobacillus casei
Lactobacillus paracasei
Lactobacillus rhamnosus
Lactococcus rhamnosus
Large-leaved linden
Lavandin
lavender
lemon balm
linalool
linden
lion's mane
lithium orotate
magnesium
magnolia
magnolol
Matcha
Melatonin
Mesembrine
Mimulus
Monoterpenes
Motherwort
Muira puama
Mulungu
N-acetyl-cysteine (NAC)
omega-3 fatty acids
passionflower
Passionfruit
phosphatidylserine
phytocannabinoids
Polygala
polygala root
prebiotic blend (proprietary)
pregnenolone
probiotics
Pulsatilla
Purple Monkeyflower
pyridoxal-5-phosphate (P-5-P)
reishi mushroom
relora® (proprietary)
Rhodiola
rosavins
rosmarinic acid
Safranal
SAMe (S-adenosyl-L-methionine disulfate p-toluensulfate)
Sandalwood
sceletium
Scleranthus annus
Shankhpushpi
shen-chu
skullcap
Spikenard
St. John's Wort
star of Bethlehem
Tea
Terpenoids
Tetrahydropalmatine
Trichilia catigua
Valerenic acid
Valerian root
velvet bean
Vervain
vitamin B
vitamin B12
vitamin B6
Vitexin
Waterhyssop
Wogonin
Yohimbine
Zinc
Other health conditions supported by linalool
Abdominal PainAnxiety
Anxiety Disorders
Arthritis
Asthma
Cancer (natural therapy for)
Colds (general)
Colds (with fever)
Congestion (bronchial)
Depression
Emotional Sensitivity
Fungal Infections
Gas and Bloating
Headache (general)
Headache (sinus)
Headache (tension)
Insomnia
Memory and Brain Function
Migraine
