Evidence supporting the use of: Linalool
For the health condition: Anxiety Disorders
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Linalool is a naturally occurring terpene alcohol found in many essential oils, including lavender and coriander. Its use to support or treat anxiety disorders is primarily supported by scientific evidence from preclinical (animal) studies and some human clinical trials, though the evidence is not yet robust or fully conclusive. Research indicates that linalool exerts anxiolytic (anxiety-reducing) effects, likely through modulation of the GABAergic system—the same neurotransmitter system targeted by many conventional anxiolytics. Animal studies consistently show that inhalation or administration of linalool reduces anxiety-like behaviors. Some small human studies and clinical trials, particularly with lavender oil preparations standardized for linalool content, report reductions in subjective anxiety and physiological markers such as heart rate and blood pressure.
However, large-scale, high-quality randomized controlled trials in humans are limited, and most of the evidence is derived from studies on essential oils containing linalool rather than the isolated compound itself. While the findings are promising and suggest a scientific basis for linalool’s anxiolytic effects, more rigorous human research is necessary to confirm efficacy, optimal dosing, and safety. Thus, the use of linalool for anxiety is classified as "scientific" with a moderate evidence rating of 3 out of 5.
Other ingredients used for Anxiety Disorders
5-Hydroxytryptophan (5-HTP)amino acids
ashwagandha
waterhyssop
beta caryophyllene
bifidobacterium infantis
bifidobacterium longum
cannabis sativa oil
chamomile
citrus oil
curcumin
ginkgo biloba
ginseng
gotu kola
green tea
hemp oil
inositol
kava root
l-glycine
l-taurine
l-theanine
l-tryptophan
lactium casein decapeptide
lactobacillus casei
lactobacillus paracasei
lactobacillus rhamnosus
lavender
lion's mane
lithium orotate
magnesium
magnolia
matcha
melatonin
motherwort
muira puama
n-acetyl-cysteine (NAC)
omega-3 fatty acids
passionflower
phosphatidylserine
phytocannabinoids
polygala root
prebiotic blend (proprietary)
pregnenolone
pyridoxal-5-phosphate (P-5-P)
reishi mushroom
relora® (proprietary)
rhodiola
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
sceletium
skullcap
valerian root
velvet bean
vitamin B
vitamin B12
vitamin B6
zinc
catnip
shen-chu
St. John's Wort
herbal blend (proprietary)
cocoa
7,8-Dihydroxyflavone
Apigenin
Albizia
Aconite
Baikal Skullcap
Bifidobacterium adolescentis
Bacopin
Brahmi
Bacopa
bacoside
Clary sage
Cymbopogon Martini
Centella asiatica
Capitate Valerian
Cowslip
Cannabidiol
Convolvulus prostratus
Convolvulus Pluricaulis
Essential Oil Blend
Spikenard
Sandalwood
Vervain
yohimbine
Other health conditions supported by Linalool
Abdominal PainAnxiety
Anxiety Disorders
Arthritis
Asthma
Cancer (natural therapy for)
Colds (general)
Colds (with fever)
Congestion (bronchial)
Depression
Emotional Sensitivity
Fungal Infections
Gas and Bloating
Headache (general)
Headache (sinus)
Headache (tension)
Insomnia
Memory and Brain Function
Migraine