Evidence supporting the use of: Oxytocin
For the health condition: Anxiety Disorders

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Oxytocin, a neuropeptide hormone often referred to as the "love hormone," has garnered scientific interest for its potential role in modulating anxiety and social behaviors. Preclinical studies in animals have shown that oxytocin can reduce anxiety-like behavior, possibly through its action on the amygdala and other stress-related brain regions. In human studies, administration of intranasal oxytocin has been found to have modest anxiolytic effects, particularly in social anxiety disorder and in facilitating social interactions. However, results across studies are mixed, and the observed effects are generally small and context-dependent. Some research suggests that oxytocin's effects may vary depending on individual differences, such as baseline anxiety levels, sex, and social context.

Systematic reviews and meta-analyses indicate that while there is scientific interest and some preliminary evidence supporting oxytocin's potential anxiolytic effects, the current body of evidence is insufficient for routine clinical use. Oxytocin is not approved by regulatory agencies for the treatment of anxiety disorders, and its off-label use is uncommon. More robust clinical trials are needed to establish efficacy, safety, dosage, and treatment protocols. Thus, while oxytocin is not used based on tradition, and there is scientific exploration, the level of validation is low (rated 2/5), and its use in anxiety disorders remains investigational.

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Products containing Oxytocin

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