Evidence supporting the use of: Probiotic (unspecified)
For the health condition: Anxiety Disorders

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

There is emerging scientific interest in the use of probiotics for supporting or treating anxiety disorders, though the evidence is still preliminary and not robust. The rationale stems from the concept of the "gut-brain axis," which is the bidirectional communication network between the gut microbiota and the central nervous system. Several small-scale clinical trials and animal studies have suggested that certain probiotic strains (such as Lactobacillus and Bifidobacterium species) may reduce symptoms of anxiety, possibly through mechanisms like modulation of inflammation, neurotransmitter production, or stress hormone regulation.

However, the quality of human evidence is limited. Most studies are small, heterogeneous, and use different probiotic strains, dosages, and durations, making it difficult to draw firm conclusions. A 2019 meta-analysis in General Psychiatry concluded that probiotics may have a mild effect in reducing anxiety symptoms, but emphasized the need for larger and more rigorous trials. Major psychiatric and medical guidelines do not currently recommend probiotics as a primary or established treatment for anxiety disorders.

In summary, while there is some scientific basis and preliminary evidence for the use of probiotics in anxiety disorders, the overall strength of evidence is low (rated 2/5), and probiotics should not be considered a substitute for established treatments. Further research is needed to determine which strains and dosages, if any, are effective.

More about Probiotic (unspecified)
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