Purple Monkeyflower (Mimulus spp.) is primarily used in the context of Bach flower remedies, a form of alternative therapy developed in the early 20th century by Edward Bach. In this system, Mimulus is designated for individuals who experience fear or anxiety about identifiable situations or things. The justification for its use in supporting or treating anxiety disorders is rooted in tradition rather than scientific validation.

There is little to no robust scientific evidence supporting the efficacy of Purple Monkeyflower for anxiety disorders. Clinical research on Bach flower remedies in general is limited and has not demonstrated significant effects beyond placebo for psychological conditions such as anxiety. Reviews and meta-analyses, including those published in peer-reviewed journals, have concluded that while flower remedies are widely used for emotional support, they lack empirical support from controlled clinical trials.

Therefore, the use of Purple Monkeyflower for anxiety remains a traditional practice based on historical and anecdotal accounts rather than scientific research. It is important for individuals seeking treatment for anxiety disorders to consult with qualified healthcare providers and rely on interventions with established efficacy.