Evidence supporting the use of: Reishi mushroom
For the health condition: Anxiety Disorders

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Reishi mushroom (Ganoderma lucidum) has a long history of use in traditional Chinese medicine, where it is considered an adaptogen—a substance believed to help the body resist stress and promote overall well-being. Historically, reishi has been used to "calm the spirit" and improve sleep, which in traditional contexts is linked to reducing anxiety and restlessness. However, direct traditional use for clinical anxiety disorders as defined by modern medicine is not clearly documented, but the general calming and stress-reducing properties are widely referenced in classical texts.

Scientific research on reishi’s effects specifically on anxiety disorders in humans is quite limited. Some preclinical studies (in animals) suggest that certain compounds in reishi, such as triterpenes and polysaccharides, may have anxiolytic (anxiety-reducing) effects, possibly through modulation of neurotransmitter systems and reduction of inflammation. However, robust clinical trials in humans are lacking, and most available human studies focus on general well-being or quality of life in cancer patients rather than specific anxiety outcomes.

In summary, while reishi mushroom is traditionally used for its calming and stress-relieving properties, there is only weak scientific evidence directly supporting its use for anxiety disorders. More high-quality clinical research is needed to substantiate its efficacy and safety for this specific indication.

More about reishi mushroom
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5-Hydroxytryptophan (5-HTP)
7,8-Dihydroxyflavone
Aconite
Albizia
amino acids
apigenin
ashwagandha
Bacopa
Bacopin
bacoside
Baikal Skullcap
beta caryophyllene
Bifidobacterium adolescentis
Bifidobacterium infantis
Bifidobacterium longum
brahmi
cannabidiol
Cannabis sativa oil
Capitate Valerian
catnip
Centella asiatica
chamomile
Clary sage
cocoa
Convolvulus pluricaulis
Convolvulus prostratus
cowslip
curcumin
Cymbopogon martini
essential oil blend
gastrodin
Gelsemium
ginkgo biloba
Ginkgoside
ginseng
gotu kola
green tea
Griffonia simplicifolia
hemp
hemp oil
herbal blend (proprietary)
hericium mushroom
Honokiol
hyperforin
Hypericum
inositol
jujubosides
kava
kavalactones
Kefir
L-glycine
L-taurine
L-theanine
L-tryptophan
lactium casein decapeptide
Lactobacillus
Lactobacillus casei
Lactobacillus paracasei
Lactobacillus rhamnosus
Lactococcus rhamnosus
Large-leaved linden
Lavandin
lavender
lemon balm
linalool
linden
lion's mane
lithium orotate
magnesium
magnolia
magnolol
Matcha
Melatonin
Mesembrine
Mimulus
Monoterpenes
Motherwort
Muira puama
Mulungu
N-acetyl-cysteine (NAC)
omega-3 fatty acids
passionflower
Passionfruit
phosphatidylserine
phytocannabinoids
Polygala
polygala root
prebiotic blend (proprietary)
pregnenolone
probiotics
Pulsatilla
Purple Monkeyflower
pyridoxal-5-phosphate (P-5-P)
reishi mushroom
relora® (proprietary)
Rhodiola
rosavins
rosmarinic acid
Safranal
SAMe (S-adenosyl-L-methionine disulfate p-toluensulfate)
Sandalwood
sceletium
Scleranthus annus
Shankhpushpi
shen-chu
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Spikenard
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Tea
Terpenoids
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velvet bean
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vitamin B
vitamin B12
vitamin B6
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