Evidence supporting the use of: Rhodiola crenulata
For the health condition: Anxiety Disorders
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Rhodiola crenulata is a species of Rhodiola traditionally used in Tibetan and Chinese medicine, often as an adaptogen to help the body cope with stress. More broadly, extracts from Rhodiola species (particularly Rhodiola rosea and Rhodiola crenulata) have been studied for their potential anxiolytic (anxiety-reducing) effects. Several small randomized controlled trials and animal studies have investigated Rhodiola's impact on symptoms of anxiety, stress, and fatigue. Some human studies have found moderate reductions in self-reported anxiety and improvements in stress-response when using standardized extracts of Rhodiola, though most of these studies have methodological limitations, such as small sample sizes, short durations, or lack of clarity on the specific Rhodiola species used.
The active compounds, such as salidroside and rosavin, are thought to modulate neurotransmitter levels (including serotonin and dopamine) and regulate the hypothalamic-pituitary-adrenal (HPA) axis. However, most clinical research focuses on R. rosea rather than R. crenulata, and direct high-quality evidence for R. crenulata in treating clinically diagnosed anxiety disorders is limited. Thus, while preliminary scientific evidence suggests some potential benefit, the quality and quantity of data are not strong enough to firmly support its use as a primary treatment for anxiety disorders. Further rigorous, large-scale studies are needed.
Other ingredients used for Anxiety Disorders
5-Hydroxytryptophan (5-HTP)amino acids
ashwagandha
waterhyssop
beta caryophyllene
bifidobacterium infantis
bifidobacterium longum
cannabis sativa oil
chamomile
citrus oil
curcumin
ginkgo biloba
ginseng
gotu kola
green tea
hemp oil
inositol
kava root
l-glycine
l-taurine
l-theanine
l-tryptophan
lactium casein decapeptide
lactobacillus casei
lactobacillus paracasei
lactobacillus rhamnosus
lavender
lion's mane
lithium orotate
magnesium
magnolia
matcha
melatonin
motherwort
muira puama
n-acetyl-cysteine (NAC)
omega-3 fatty acids
passionflower
phosphatidylserine
phytocannabinoids
polygala root
prebiotic blend (proprietary)
pregnenolone
pyridoxal-5-phosphate (P-5-P)
reishi mushroom
relora® (proprietary)
rhodiola
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
sceletium
skullcap
valerian root
velvet bean
vitamin B
vitamin B12
vitamin B6
zinc
catnip
shen-chu
St. John's Wort
herbal blend (proprietary)
cocoa
7,8-Dihydroxyflavone
Apigenin
Albizia
Aconite
Baikal Skullcap
Bifidobacterium adolescentis
Bacopin
Brahmi
Bacopa
bacoside
Clary sage
Cymbopogon Martini
Centella asiatica
Capitate Valerian
Cowslip
Cannabidiol
Convolvulus prostratus
Convolvulus Pluricaulis
Essential Oil Blend
Spikenard
Sandalwood
Vervain
yohimbine
Other health conditions supported by Rhodiola crenulata
Adrenal FatigueAging (prevention)
Anxiety
Anxiety Disorders
Athletic and Exercise Aids
Concentration (poor)
Depression
Energy (lack of)
Fatigue
Memory and Brain Function
Stress