Evidence supporting the use of: Serotonin
For the health condition: Anxiety Disorders
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Serotonin is a neurotransmitter that plays a key role in mood regulation, and there is robust scientific evidence linking serotonin levels to anxiety disorders. Many pharmacological treatments for anxiety, such as selective serotonin reuptake inhibitors (SSRIs), are designed to increase serotonin activity in the brain. Numerous clinical trials and meta-analyses have demonstrated that SSRIs are effective in reducing symptoms of various anxiety disorders, including generalized anxiety disorder, social anxiety disorder, and panic disorder. This therapeutic effect is believed to be due to the enhancement of serotonergic neurotransmission, which helps modulate mood and anxiety levels.
However, it is important to note that exogenous serotonin (e.g., taking serotonin directly as a supplement) is not used clinically for anxiety disorders because serotonin itself does not cross the blood-brain barrier effectively. Instead, medications that increase the availability or action of serotonin within the brain are the standard of care. Thus, while direct supplementation with serotonin is not practiced, the scientific rationale for targeting the serotonin system in the treatment of anxiety disorders is well-established and supported by decades of research.
Other ingredients used for Anxiety Disorders
5-Hydroxytryptophan (5-HTP)amino acids
ashwagandha
waterhyssop
beta caryophyllene
bifidobacterium infantis
bifidobacterium longum
cannabis sativa oil
chamomile
citrus oil
curcumin
ginkgo biloba
ginseng
gotu kola
green tea
hemp oil
inositol
kava root
l-glycine
l-taurine
l-theanine
l-tryptophan
lactium casein decapeptide
lactobacillus casei
lactobacillus paracasei
lactobacillus rhamnosus
lavender
lion's mane
lithium orotate
magnesium
magnolia
matcha
melatonin
motherwort
muira puama
n-acetyl-cysteine (NAC)
omega-3 fatty acids
passionflower
phosphatidylserine
phytocannabinoids
polygala root
prebiotic blend (proprietary)
pregnenolone
pyridoxal-5-phosphate (P-5-P)
reishi mushroom
relora® (proprietary)
rhodiola
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
sceletium
skullcap
valerian root
velvet bean
vitamin B
vitamin B12
vitamin B6
zinc
catnip
shen-chu
St. John's Wort
herbal blend (proprietary)
cocoa
7,8-Dihydroxyflavone
Apigenin
Albizia
Aconite
Baikal Skullcap
Bifidobacterium adolescentis
Bacopin
Brahmi
Bacopa
bacoside
Clary sage
Cymbopogon Martini
Centella asiatica
Capitate Valerian
Cowslip
Cannabidiol
Convolvulus prostratus
Convolvulus Pluricaulis
Essential Oil Blend
Spikenard
Sandalwood
Vervain
yohimbine
Other health conditions supported by Serotonin
AnxietyAnxiety Disorders
Depression
Mood Swings
Seasonal Affective Disorder