Evidence supporting the use of: Terpenoids
For the health condition: Anxiety Disorders

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Terpenoids, also known as isoprenoids, are a large and diverse class of naturally occurring organic chemicals derived from terpenes. They are found in many plants, including those used in traditional herbal remedies for anxiety, such as lavender and cannabis. Scientific interest in terpenoids has grown due to their presence in essential oils and their potential effects on the central nervous system.

Several terpenoids, such as linalool (found in lavender) and beta-caryophyllene (found in black pepper and cannabis), have been studied for their anxiolytic (anxiety-reducing) properties. Preclinical studies, primarily in animal models, suggest that some terpenoids may modulate neurotransmitter systems involved in anxiety, such as the GABAergic and endocannabinoid systems. For example, linalool has demonstrated anxiolytic-like effects in rodents, which may be mediated by interactions with GABAA receptors. Beta-caryophyllene has shown similar effects, potentially via CB2 receptor activation.

However, human clinical evidence remains limited. Most studies are small, preliminary, or based on inhalation of essential oils rather than isolated terpenoids. While traditional use and animal studies provide a rationale for further research, current scientific evidence supporting the use of terpenoids for anxiety disorders in humans is low to moderate. Well-designed clinical trials are needed to confirm both efficacy and safety.

More about Terpenoids
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Other ingredients used for Anxiety Disorders

5-Hydroxytryptophan (5-HTP)
7,8-Dihydroxyflavone
Aconite
Albizia
amino acids
apigenin
ashwagandha
Bacopa
Bacopin
bacoside
Baikal Skullcap
beta caryophyllene
Bifidobacterium adolescentis
Bifidobacterium infantis
Bifidobacterium longum
brahmi
cannabidiol
Cannabis sativa oil
Capitate Valerian
catnip
Centella asiatica
chamomile
Clary sage
cocoa
Convolvulus pluricaulis
Convolvulus prostratus
cowslip
curcumin
Cymbopogon martini
essential oil blend
gastrodin
Gelsemium
ginkgo biloba
Ginkgoside
ginseng
gotu kola
green tea
Griffonia simplicifolia
hemp
hemp oil
herbal blend (proprietary)
hericium mushroom
Honokiol
hyperforin
Hypericum
inositol
jujubosides
kava
kavalactones
Kefir
L-glycine
L-taurine
L-theanine
L-tryptophan
lactium casein decapeptide
Lactobacillus
Lactobacillus casei
Lactobacillus paracasei
Lactobacillus rhamnosus
Lactococcus rhamnosus
Large-leaved linden
Lavandin
lavender
lemon balm
linalool
linden
lion's mane
lithium orotate
magnesium
magnolia
magnolol
Matcha
Melatonin
Mesembrine
Mimulus
Monoterpenes
Motherwort
Muira puama
Mulungu
N-acetyl-cysteine (NAC)
omega-3 fatty acids
passionflower
Passionfruit
phosphatidylserine
phytocannabinoids
Polygala
polygala root
prebiotic blend (proprietary)
pregnenolone
probiotics
Pulsatilla
Purple Monkeyflower
pyridoxal-5-phosphate (P-5-P)
reishi mushroom
relora® (proprietary)
Rhodiola
rosavins
rosmarinic acid
Safranal
SAMe (S-adenosyl-L-methionine disulfate p-toluensulfate)
Sandalwood
sceletium
Scleranthus annus
Shankhpushpi
shen-chu
skullcap
Spikenard
St. John's Wort
star of Bethlehem
Tea
Terpenoids
Tetrahydropalmatine
Trichilia catigua
Valerenic acid
Valerian root
velvet bean
Vervain
vitamin B
vitamin B12
vitamin B6
Vitexin
Waterhyssop
Wogonin
Yohimbine
Zinc

Products containing Terpenoids

We currently have no products on Vitabase that contain this ingredient.