Evidence supporting the use of: Valerian root
For the health condition: Anxiety Disorders

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Valerian root (Valeriana officinalis) has a long history of use in traditional herbal medicine, particularly in Europe and Asia, as a remedy for anxiety, insomnia, and nervous tension. Its use for anxiety dates back to ancient Greece and Rome, where physicians such as Hippocrates described its calming effects. The root was commonly used in traditional European medicine throughout the Middle Ages and into the modern era for "nervous disorders" and as a general sedative.

Modern scientific studies evaluating valerian root for anxiety are limited and have produced mixed results. Some small-scale clinical trials suggest that valerian may have mild anxiolytic (anxiety-reducing) effects, possibly due to its interaction with gamma-aminobutyric acid (GABA) receptors in the brain, which are involved in regulating nervous system activity. However, systematic reviews and meta-analyses generally conclude that the evidence is insufficient or inconsistent to firmly support valerian's effectiveness for treating anxiety disorders. Most studies have small sample sizes, short durations, and methodological limitations.

In summary, valerian root is used for anxiety primarily due to its traditional use, with weak to moderate scientific evidence supporting its efficacy. While it appears to be relatively safe for most people, those considering valerian for anxiety should consult with a healthcare professional due to possible interactions and side effects.

More about Valerian root
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Other ingredients used for Anxiety Disorders

5-Hydroxytryptophan (5-HTP)
7,8-Dihydroxyflavone
Aconite
Albizia
amino acids
apigenin
ashwagandha
Bacopa
Bacopin
bacoside
Baikal Skullcap
beta caryophyllene
Bifidobacterium adolescentis
Bifidobacterium infantis
Bifidobacterium longum
brahmi
cannabidiol
Cannabis sativa oil
Capitate Valerian
catnip
Centella asiatica
chamomile
Clary sage
cocoa
Convolvulus pluricaulis
Convolvulus prostratus
cowslip
curcumin
Cymbopogon martini
essential oil blend
gastrodin
Gelsemium
ginkgo biloba
Ginkgoside
ginseng
gotu kola
green tea
Griffonia simplicifolia
hemp
hemp oil
herbal blend (proprietary)
hericium mushroom
Honokiol
hyperforin
Hypericum
inositol
jujubosides
kava
kavalactones
Kefir
L-glycine
L-taurine
L-theanine
L-tryptophan
lactium casein decapeptide
Lactobacillus
Lactobacillus casei
Lactobacillus paracasei
Lactobacillus rhamnosus
Lactococcus rhamnosus
Large-leaved linden
Lavandin
lavender
lemon balm
linalool
linden
lion's mane
lithium orotate
magnesium
magnolia
magnolol
Matcha
Melatonin
Mesembrine
Mimulus
Monoterpenes
Motherwort
Muira puama
Mulungu
N-acetyl-cysteine (NAC)
omega-3 fatty acids
passionflower
Passionfruit
phosphatidylserine
phytocannabinoids
Polygala
polygala root
prebiotic blend (proprietary)
pregnenolone
probiotics
Pulsatilla
Purple Monkeyflower
pyridoxal-5-phosphate (P-5-P)
reishi mushroom
relora® (proprietary)
Rhodiola
rosavins
rosmarinic acid
Safranal
SAMe (S-adenosyl-L-methionine disulfate p-toluensulfate)
Sandalwood
sceletium
Scleranthus annus
Shankhpushpi
shen-chu
skullcap
Spikenard
St. John's Wort
star of Bethlehem
Tea
Terpenoids
Tetrahydropalmatine
Trichilia catigua
Valerenic acid
Valerian root
velvet bean
Vervain
vitamin B
vitamin B12
vitamin B6
Vitexin
Waterhyssop
Wogonin
Yohimbine
Zinc