Evidence supporting the use of: Valerian root
For the health condition: Anxiety Disorders

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Valerian root (Valeriana officinalis) has a long history of use in traditional herbal medicine, particularly in Europe and Asia, as a remedy for anxiety, insomnia, and nervous tension. Its use for anxiety dates back to ancient Greece and Rome, where physicians such as Hippocrates described its calming effects. The root was commonly used in traditional European medicine throughout the Middle Ages and into the modern era for "nervous disorders" and as a general sedative.

Modern scientific studies evaluating valerian root for anxiety are limited and have produced mixed results. Some small-scale clinical trials suggest that valerian may have mild anxiolytic (anxiety-reducing) effects, possibly due to its interaction with gamma-aminobutyric acid (GABA) receptors in the brain, which are involved in regulating nervous system activity. However, systematic reviews and meta-analyses generally conclude that the evidence is insufficient or inconsistent to firmly support valerian's effectiveness for treating anxiety disorders. Most studies have small sample sizes, short durations, and methodological limitations.

In summary, valerian root is used for anxiety primarily due to its traditional use, with weak to moderate scientific evidence supporting its efficacy. While it appears to be relatively safe for most people, those considering valerian for anxiety should consult with a healthcare professional due to possible interactions and side effects.

More about valerian root
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5-Hydroxytryptophan (5-HTP)
amino acids
ashwagandha
waterhyssop
beta caryophyllene
bifidobacterium infantis
bifidobacterium longum
cannabis sativa oil
chamomile
citrus oil
curcumin
ginkgo biloba
ginseng
gotu kola
green tea
hemp oil
inositol
kava
L-glycine
L-taurine
L-theanine
L-tryptophan
lactium casein decapeptide
lactobacillus casei
lactobacillus paracasei
lactobacillus rhamnosus
lavender
lion's mane
lithium orotate
magnesium
magnolia
matcha
melatonin
motherwort
muira puama
n-acetyl-cysteine (NAC)
omega-3 fatty acids
passionflower
phosphatidylserine
phytocannabinoids
polygala root
prebiotic blend (proprietary)
pregnenolone
pyridoxal-5-phosphate (P-5-P)
reishi mushroom
relora® (proprietary)
rhodiola
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
sceletium
skullcap
valerian root
velvet bean
vitamin B
vitamin B12
vitamin B6
zinc
catnip
shen-chu
St. John's Wort
herbal blend (proprietary)
cocoa
star of Bethlehem
7,8-Dihydroxyflavone
Apigenin
Albizia
Aconite
Baikal Skullcap
Bifidobacterium adolescentis
Bacopin
Brahmi
Bacopa
bacoside
Clary sage
Cymbopogon Martini
Centella asiatica
Capitate Valerian
Cowslip
Cannabidiol
Convolvulus prostratus
Convolvulus Pluricaulis
Essential Oil Blend
Gelsemium
Griffonia simplicifolia
Ginkgoside
Gastrodin
Honokiol
Hypericum
hyperforin
Hericium mushroom
Hemp
Jujubosides
Kavalactones
Kefir
lemon balm
Linden
Lactococcus rhamnosus
Lavandin
Large-Leaved Linden
Lactobacillus
Linalool
Mimulus
Monoterpenes
Magnolol
Mulungu
Mesembrine
Pulsatilla
Probiotics
Passionfruit
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Purple Monkeyflower
Rosavins
Rosmarinic Acid
Spikenard
Scleranthus annus
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yohimbine