Evidence supporting the use of: Albizia julibrissin
For the health condition: Apathy

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Albizia julibrissin, commonly known as the Persian silk tree or mimosa, has a long history of use in traditional Chinese medicine (TCM), where it is known as "He Huan Pi" (the bark) or "He Huan Hua" (the flower). In TCM, it is traditionally used to "calm the spirit," relieve emotional constraint, alleviate sadness, and treat conditions such as anxiety, insomnia, and apathy. The rationale for its use in apathy stems from its application for emotional disturbances, particularly where a lack of motivation or flat affect is present. The traditional literature describes it as a remedy to "lift the mood" and "open the heart," which aligns conceptually with addressing apathy.

Scientific evidence for its use in apathy specifically is limited. Some preclinical studies suggest neuroprotective, anxiolytic, and antidepressant effects, possibly via modulation of neurotransmitters, but robust clinical trials in humans targeting apathy are lacking. Thus, its use for apathy is justified by tradition rather than strong scientific validation, and the evidence rating reflects reliance on historical rather than modern clinical data.

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