Relationship: Arteries and EPA (eicosapentaenoic acid)

Evidence supporting the use of: EPA (eicosapentaenoic acid)
For the body system: Arteries

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Eicosapentaenoic acid (EPA) is an omega-3 polyunsaturated fatty acid primarily found in fish oil. There is substantial scientific evidence supporting its use for arterial health. EPA has been shown to help lower triglyceride levels, reduce inflammation, and improve endothelial function—all factors that contribute to arterial health and decreased risk of atherosclerosis. Several large clinical trials and meta-analyses have examined the cardiovascular benefits of omega-3 fatty acids, including EPA. For example, the REDUCE-IT trial (2018) demonstrated that high-dose purified EPA (icosapent ethyl) significantly reduced the risk of major cardiovascular events in patients with elevated triglycerides and existing cardiovascular risk factors. Mechanistically, EPA is thought to exert its benefits by reducing the production of pro-inflammatory eicosanoids, improving lipid profiles, and possibly stabilizing atherosclerotic plaques. While some studies have shown mixed results regarding the extent of cardiovascular benefit, the overall body of evidence supports a positive effect of EPA on arterial health, especially in populations at increased risk for cardiovascular disease. Thus, the use of EPA to support the arteries is primarily justified by scientific research rather than tradition.

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alpha-linolenic acid (ALA)
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Other body systems supported by EPA (eicosapentaenoic acid)

Arteries
Blood
Brain
Circulatory System
Eyes
Heart
Immune System
Intestinal System
Joints
Liver
Lungs
Prostaglandins
Reproductive System
Respiratory System
Skin

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Health Concerns

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Evidence supporting the use of: EPA (eicosapentaenoic acid)
For the body system: Arteries

Table of Contents

Synopsis

Other ingredients that support Arteries

Other body systems supported by EPA (eicosapentaenoic acid)

Products containing EPA (eicosapentaenoic acid)

Health Concerns

Brands

Evidence supporting the use of: EPA (eicosapentaenoic acid)For the body system: Arteries

Table of Contents

Synopsis

Other ingredients that support Arteries

Other body systems supported by EPA (eicosapentaenoic acid)

Products containing EPA (eicosapentaenoic acid)

Evidence supporting the use of: EPA (eicosapentaenoic acid)
For the body system: Arteries