Evidence supporting the use of: Flavonoids
For the body system: Arteries
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Flavonoids are a diverse group of plant compounds found abundantly in fruits, vegetables, tea, and cocoa. Their use to support arterial health is primarily supported by scientific evidence. Numerous epidemiological studies have linked higher dietary intake of flavonoids with a reduced risk of cardiovascular diseases, including atherosclerosis, which directly involves the arteries. Mechanistically, flavonoids are known to exert antioxidant, anti-inflammatory, and vasodilatory effects. They help reduce oxidative stress and inflammation in the vascular endothelium, which are key contributors to arterial dysfunction and plaque formation.
Clinical trials have demonstrated that certain flavonoids, such as those found in cocoa, citrus fruits, and berries, can improve endothelial function (the lining of the arteries), lower blood pressure, and reduce LDL cholesterol oxidation. For example, a meta-analysis published in the American Journal of Clinical Nutrition (2012) concluded that flavonoid-rich cocoa products improved flow-mediated dilation, a marker of arterial health. Similarly, studies on quercetin and hesperidin, specific types of flavonoids, show improvements in blood pressure and arterial stiffness.
While more extensive clinical trials are warranted, the current body of evidence provides substantial scientific validation for the use of flavonoids in supporting arterial health, justifying a high evidence rating.
Other ingredients that support Arteries
ajoenealgal oil
alpha-linolenic acid (ALA)
amino acids
anchovies
anthocyanins
apple
arjun tree
artichoke
astaxanthin
barley
beet
bergamot
bilberry
black cumin
black currant
black garlic
sesame
black tea
blackberry
blueberry
bonito peptide
Indian frankincense
broccoli
brussel sprouts
butcher's broom
calamari oil
campesterol
canola oil
capsaicinoids
catechins
celery
cherry
chia seed
Chinese salvia root
chokeberry
cinnamon
citrus bioflavonoids
citrus pectin
citrus sinensis (proprietary)
coenzyme Q10 (CoQ10)
turmeric
curcumin
d-alpha tocopherol
DHA (docosahexaeonic acid)
diallyl disulfide (DADS)
diallyl trisulfide (DATS)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
ethanol
fiber blend (proprietary)
fish oil
fish protein
flavonols
flaxseed
fruit and vegetable blend (proprietary)
fruit blend (proprietary)
gamma tocopherol
garlic bulb
ginger
ginkgo biloba
ginseng
gooseberry
gotu kola
grape
onion
green tea
guggul
hawthorn
hawthorn
hesperetin
hesperidin
hibiscus
horse chestnut
knotweed
kale
krill oil
l-arginine
l-citrulline
lemon
lignans
linoleic acid (LA)
lycopene
mackerel
magnesium
marine lipid
matcha
moringa
motherwort
mustard seed
naringin
nattokinase
niacin (vitamin B3)
niacinamide (vitamin B3)
oleic acid
olive
omega-3 fatty acids
omega-6 fatty acids
omega-7 fatty acids
omega-9 fatty acids
orange
palmitoleic acid
phenolic acids
phytosterols
pine bark
plant sterols
pomegranate
potassium
pumpkin
quercetin
red yeast rice
resveratrol
rose hips
rosemary
rutin
safflower oil
sardines
black ginger
sitostanol
soybean
spinach
sterols
strawberry
tocotrienols
tomato
trans-pterostilbene
almond fruit
ubiquinol
vegetable and fruit blend (proprietary)
vitamin B
vitamin C
vitamin D
vitamin E
vitamin K
seaweed
water
watercress
watermelon
mulberry
zinc
jiaogulan
capsicum
inula racemosa
commiphora
lingzhi
lingusticum wallichii
yarrow
prickly ash
morus
sodium salt
ferulic acid
eucommia
ganoderma
electrolytes blend (proprietary)
terpene lactones
polyphenols
trace minerals
purslane
shepherd's purse
yerba mate
noni
amaranth
herbal blend (proprietary)
algae
cocoa
cayenne pepper
Arjuna
Arginine Alpha Ketoglutarate
Arginine nitrate
Asiaticoside
Aronia melanocarpa
Allicin
Arginine malate
Arginine aspartate
Auricularia
Avocado
Adrenergic amines
Alpha-Lipoic Acid
Adrenaline
Aescin
anthocyanidins
Alpha phytosterol
Acetylsalicylic acid
Arjunic Acid
Alliin
anthocyanosides
Allium tuberosum
Apocynin
Arginine silicate
Arjunolic acid
Black Seed
Butylphthalide
Baikal Skullcap
Bidens pilosa
Brutieridin
Brown Algae
Brassica
Bishop's Weed
Bran
Baccharis dracunculifolia
Berberis (unspecified)
Bok Choy
Baicalein
Betanin
berry
Bioflavonoids
Baicalin
Buckwheat
Bignay
Chia seed
Camellia sinensis
Cinnamomum
Capsinoids
Camelina Oil
Cod Liver Oil
Cyathula
Cyanidin
chlorogenic acid
Curcuminoid
Citrus
Capsaicin
Catecholamine
Cruciferous
Chocolate
Curcuma
Carnosol
Calanus finmarchicus
cypress
Chestnut
Crocetin
Collinsonia
Carthamus
Casearia sylvestris
Docosahexaenoic Acid
Diallyl sulfide
Diosmin
Danshen
Delphinidin
Dulse
Diosmetin
epicatechin
Ellagic Acid
Eriocitrin
Egg
Emblicanin
Eicosapentaenoic Acid
Escin
Eucommia ulmoides
Elastin
Ellagitannin
Flavonoids
Flavonones
fibroblast growth factor
Garlic
Pistachio
walnut