Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Hydroxytyrosol is a phenolic compound predominantly found in olives and olive oil. Its use to support arterial and cardiovascular health is justified by a growing body of scientific evidence, though the majority comes from preclinical studies and small-scale clinical trials rather than large, definitive randomized controlled trials. Hydroxytyrosol exhibits potent antioxidant and anti-inflammatory properties, which are believed to protect the endothelium (the inner lining of blood vessels) from oxidative stress and inflammation—both key contributors to atherosclerosis and arterial dysfunction.

Several in vitro and animal studies have demonstrated that hydroxytyrosol can reduce oxidative damage to LDL cholesterol, a key driver of plaque formation in arteries. Human clinical evidence, while limited, includes studies showing that consumption of olive oil rich in hydroxytyrosol leads to improved markers of endothelial function and reduced biomarkers of oxidative stress. The European Food Safety Authority (EFSA) has acknowledged that hydroxytyrosol and its derivatives contribute to the protection of blood lipids from oxidative damage when olive oil contains at least 5 mg of hydroxytyrosol and its derivatives per 20 g of oil.

In summary, while more large-scale human trials are needed, the current scientific evidence supports the role of hydroxytyrosol in supporting arterial health, primarily via its antioxidant effects. Thus, its use is scientifically justified, but the strength of evidence is moderate (rated 3/5).

More about hydroxytyrosol
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Other ingredients that support Arteries

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algal oil
Allicin
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Allium tuberosum
Almond fruit
Alpha phytosterol
alpha-linolenic acid (ALA)
alpha-lipoic acid
amaranth
amino acids
anchovies
anthocyanidins
anthocyanins
anthocyanosides
apocynin
apple
arginine alpha ketoglutarate
Arginine aspartate
Arginine malate
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Arginine silicate
arjun tree
arjuna
arjunic acid
Arjunolic acid
Aronia melanocarpa
artichoke
asiaticoside
astaxanthin
Auricularia
avocado
Baccharis dracunculifolia
baicalein
baicalin
Baikal Skullcap
barley
beet
Berberis (unspecified)
bergamot
berry
betanin
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bignay
bilberry
bioflavonoids
bishop\'s weed
black cumin
black currant
black garlic
black ginger
black seed
black tea
blackberry
blueberry
bok choy
bonito peptide
bran
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brutieridin
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butcher's broom
butylphthalide
calamari oil
Calanus finmarchicus
camelina oil
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campesterol
capsaicin
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capsicum
capsinoids
carnosol
Carthamus
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catechins
catecholamine
cayenne pepper
celery
cherry
chestnut
chia seed
chia seed
Chinese salvia root
chlorogenic acid
chocolate
chokeberry
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cinnamon
Citrus
citrus bioflavonoids
citrus pectin
citrus sinensis (proprietary)
cocoa
cod liver oil
coenzyme Q10 (CoQ10)
Collinsonia
commiphora
crocetin
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curcumin
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cyanidin
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cypress
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hesperidin
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lingzhi
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linseed oil
lipids
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lumbrokinase
lycopene
magnesium
malvidin
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Marine fat
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Methylxanthine
Mineral ascorbate
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mustard seed
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omega-7 fatty acids
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onion
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pagoda tree
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pine bark
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Other body systems supported by hydroxytyrosol

Arteries
Blood
Brain
Circulatory System
Heart
Immune System
Liver
Skin

Products containing hydroxytyrosol

We currently have no products on Vitabase that contain this ingredient.