Evidence supporting the use of: Methylxanthine (unspecified)
For the body system: Arteries

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Methylxanthines—a class of compounds including caffeine, theobromine, and theophylline—are known for their stimulant effects and are found in common foods and beverages such as coffee, tea, and chocolate. Their relationship to the arteries and cardiovascular system has been the subject of numerous studies. Methylxanthines exert several physiological effects, including vasodilation (widening of blood vessels), mild diuresis, and increased heart rate, primarily through antagonism of adenosine receptors and inhibition of phosphodiesterase enzymes.

Regarding the arteries specifically, certain methylxanthines (notably theophylline and aminophylline) have been shown to relax smooth muscle in blood vessel walls, leading to vasodilation. This effect can temporarily reduce arterial resistance and improve blood flow. Caffeine, the most widely consumed methylxanthine, has complex effects: it can cause mild acute increases in blood pressure, but regular coffee consumption has not been definitively linked to long-term arterial damage or increased arterial stiffness in healthy individuals. Some studies suggest potential protective effects on endothelial function and arterial health due to antioxidant and anti-inflammatory properties of coffee and tea, though findings are mixed and context-dependent.

In summary, there is moderate scientific evidence (rating 3/5) that methylxanthines influence arterial function, primarily through vasodilation and modulation of vascular tone. However, these effects are not uniformly beneficial, and the clinical use of methylxanthines to "support" arterial health is limited. Their impact can vary based on dosage, individual health status, and specific methylxanthine compound.

More about Methylxanthine (unspecified)
More about Arteries

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Products containing Methylxanthine (unspecified)

We currently have no products on Vitabase that contain this ingredient.