Evidence supporting the use of: Omega-3
For the body system: Arteries

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Omega-3 fatty acids, particularly EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), have scientific validation for their role in supporting arterial and cardiovascular health. Numerous randomized controlled trials and meta-analyses have shown that Omega-3s can reduce triglyceride levels, modestly lower blood pressure, decrease inflammation, and improve endothelial function—all factors important for arterial health. For example, the American Heart Association recommends Omega-3 fatty acids for reducing the risk of cardiovascular disease, citing evidence from studies like the GISSI-Prevenzione trial, which found that supplementation reduced cardiovascular events in patients with previous myocardial infarction. Further, Omega-3s may reduce arterial stiffness and slow the progression of atherosclerosis, as demonstrated in studies using carotid intima-media thickness as a marker. However, the benefits are most significant for secondary prevention (those with existing heart disease) and in lowering triglyceride levels, rather than for primary prevention in the general population. Overall, the scientific community recognizes a moderate to strong evidence base for Omega-3s in supporting arterial health, especially through their lipid-lowering and anti-inflammatory effects.

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Products containing Omega-3

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