Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Proanthocyanidins are a class of polyphenolic compounds found in various plants, especially in grape seeds, pine bark, and certain berries. Their use to support arterial health is primarily based on scientific evidence, though not all claims are equally substantiated. Several studies have investigated their vascular effects, focusing on their antioxidant, anti-inflammatory, and endothelial-protective properties.

Research indicates that proanthocyanidins can help protect arteries by reducing oxidative stress, inhibiting LDL cholesterol oxidation, and improving endothelial function. For instance, grape seed extract, rich in proanthocyanidins, has been shown in some randomized controlled trials to reduce blood pressure and improve markers of arterial function. These compounds may enhance nitric oxide availability, leading to improved vasodilation and thus healthier arterial function.

Meta-analyses of clinical trials suggest modest benefits in lowering blood pressure and improving vascular elasticity, though results can be inconsistent depending on the population and dosage. Animal and in vitro studies further support mechanisms by which proanthocyanidins might protect against atherosclerotic changes. However, more large-scale, high-quality human trials are needed to confirm clinical significance and optimal dosing.

In summary, there is scientific evidence, though not conclusive, supporting the use of proanthocyanidins for arterial support, primarily due to their antioxidant and vasoactive actions. The evidence base rates as moderate (3/5), with ongoing research likely to clarify their role in arterial health.

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Other ingredients that support Arteries

ajoene
algal oil
alpha-linolenic acid (ALA)
amino acids
anchovies
anthocyanins
apple
arjun tree
artichoke
astaxanthin
barley
beet
bergamot
bilberry
black cumin
black currant
black garlic
sesame
black tea
blackberry
blueberry
bonito peptide
Indian frankincense
broccoli
brussel sprouts
butcher's broom
calamari oil
campesterol
canola oil
capsaicinoids
catechins
celery
cherry
chia seed
Chinese salvia root
chokeberry
cinnamon
citrus bioflavonoids
citrus pectin
citrus sinensis (proprietary)
coenzyme Q10 (CoQ10)
turmeric
curcumin
d-alpha tocopherol
DHA (docosahexaeonic acid)
diallyl disulfide (DADS)
diallyl trisulfide (DATS)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
ethanol
fiber blend (proprietary)
fish oil
fish protein
flavonols
flaxseed
fruit and vegetable blend (proprietary)
fruit blend (proprietary)
gamma tocopherol
garlic bulb
ginger
ginkgo biloba
ginseng
gooseberry
gotu kola
grape
onion
green tea
guggul
hawthorn
hawthorn
hesperetin
hesperidin
hibiscus
horse chestnut
knotweed
kale
krill oil
l-arginine
l-citrulline
lemon
lignans
linoleic acid (LA)
lycopene
mackerel
magnesium
marine lipid
matcha
moringa
motherwort
mustard seed
naringin
nattokinase
niacin (vitamin B3)
niacinamide (vitamin B3)
oleic acid
olive
omega-3 fatty acids
omega-6 fatty acids
omega-7 fatty acids
omega-9 fatty acids
orange
palmitoleic acid
phenolic acids
phytosterols
pine bark
plant sterols
pomegranate
potassium
pumpkin
quercetin
red yeast rice
resveratrol
rose hips
rosemary
rutin
safflower oil
sardines
black ginger
sitostanol
soybean
spinach
sterols
strawberry
tocotrienols
tomato
trans-pterostilbene
almond fruit
ubiquinol
vegetable and fruit blend (proprietary)
vitamin B
vitamin C
vitamin D
vitamin E
vitamin K
seaweed
water
watercress
watermelon
mulberry
zinc
jiaogulan
capsicum
inula racemosa
commiphora
lingzhi
lingusticum wallichii
yarrow
prickly ash
morus
sodium salt
ferulic acid
eucommia
ganoderma
electrolytes blend (proprietary)
terpene lactones
polyphenols
trace minerals
purslane
shepherd's purse
yerba mate
noni
amaranth
herbal blend (proprietary)
algae
cocoa
cayenne pepper
Arjuna
Arginine Alpha Ketoglutarate
Arginine nitrate
Asiaticoside
Aronia melanocarpa
Allicin
Arginine malate
Arginine aspartate
Auricularia
Avocado
Adrenergic amines
Alpha-Lipoic Acid
Adrenaline
Aescin
anthocyanidins
Alpha phytosterol
Acetylsalicylic acid
Arjunic Acid
Alliin
anthocyanosides
Allium tuberosum
Apocynin
Arginine silicate
Arjunolic acid
Black Seed
Butylphthalide
Baikal Skullcap
Bidens pilosa
Brutieridin
Brown Algae
Brassica
Bishop's Weed
Bran
Baccharis dracunculifolia
Berberis (unspecified)
Bok Choy
Baicalein
Betanin
berry
Bioflavonoids
Baicalin
Buckwheat
Bignay
Chia seed
Camellia sinensis
Cinnamomum
Capsinoids
Camelina Oil
Cod Liver Oil
Cyathula
Cyanidin
chlorogenic acid
Curcuminoid
Citrus
Capsaicin
Catecholamine
Cruciferous
Chocolate
Curcuma
Carnosol
Calanus finmarchicus
cypress
Chestnut
Crocetin
Collinsonia
Carthamus
Casearia sylvestris
Docosahexaenoic Acid
Diallyl sulfide
Diosmin
Danshen
Delphinidin
Dulse
Diosmetin
epicatechin
Ellagic Acid
Eriocitrin
Egg
Emblicanin
Eicosapentaenoic Acid
Escin
Eucommia ulmoides
Elastin
Ellagitannin
Flavonoids
Flavonones
fibroblast growth factor
Garlic
Pistachio
walnut

Other body systems supported by Proanthocyanidins

Arteries
Blood
Capillaries
Circulatory System
Eyes
Gastrointestinal Tract
Gums
Heart
Immune System
Skin
Urinary System
Veins

Products containing Proanthocyanidins

We currently have no products on Vitabase that contain this ingredient.