Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Rauvolfia vomitoria has a long history of traditional use in African herbal medicine, including for cardiovascular health concerns. Traditional healers have used its root extracts for managing conditions such as hypertension and nervous system disorders. The primary bioactive compound, reserpine, is known to lower blood pressure by depleting catecholamines (such as norepinephrine) from sympathetic nerve endings, thus reducing arterial tension. This mechanism led to the Western pharmaceutical adoption of reserpine, initially isolated from Rauvolfia serpentina, for antihypertensive therapy in the mid-20th century. Rauvolfia vomitoria contains similar indole alkaloids, and its use for hypertension is documented in ethnobotanical literature.

However, while there is a clear basis in traditional practices, robust modern clinical trials specifically evaluating Rauvolfia vomitoria for arterial or cardiovascular health are limited. Most of the pharmacological data and clinical research relate to Rauvolfia serpentina, with some overlap in constituent compounds. Potential side effects, including depression and extrapyramidal symptoms, have limited the use of Rauvolfia-derived medications in modern medicine. Therefore, while the traditional use is well established and there is a pharmacological rationale, scientific validation in the context of clinical trials for Rauvolfia vomitoria itself remains limited.

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Other body systems supported by Rauvolfia vomitoria

Arteries
Blood
Brain
Circulatory System
Dopamine
Heart
Nerves
Parasympathetic Nervous System

Products containing Rauvolfia vomitoria

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