Evidence supporting the use of: Stilbenoid
For the body system: Arteries

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Stilbenoids are a class of polyphenolic compounds, the most well-known of which is resveratrol, found in grapes, berries, and peanuts. Scientific interest in stilbenoids, especially resveratrol, centers on their potential cardiovascular benefits. Several preclinical studies and some human clinical trials have investigated their effects on arterial health. Stilbenoids exhibit antioxidant and anti-inflammatory properties, which are believed to contribute to improved endothelial function and reduced arterial stiffness. Resveratrol, for example, has been shown to enhance nitric oxide production, improve vascular relaxation, and inhibit the oxidation of low-density lipoprotein (LDL) cholesterol—factors critical to arterial health. Some small clinical studies have reported modest improvements in blood pressure and arterial function in humans supplemented with resveratrol. However, most evidence comes from animal models or in vitro studies, and human data remain preliminary and sometimes inconsistent. While there is a scientific rationale and some early clinical support for the use of stilbenoids to support arterial health, robust, large-scale human trials are lacking. Thus, the evidence base is moderate, and further research is needed to establish definitive benefits and optimal dosing.

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Products containing Stilbenoid

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