Evidence supporting the use of: Sulfated polysaccharide
For the body system: Arteries

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Sulfated polysaccharides, such as those found in seaweeds (e.g., fucoidan, carrageenan, ulvan), have been studied for their potential cardiovascular benefits, including support for arterial health. Scientific research, particularly from in vitro and animal studies, suggests that these compounds can exert anticoagulant, antithrombotic, and anti-inflammatory effects, which are relevant to arterial function and health. For example, fucoidan has been shown to inhibit platelet aggregation and reduce blood clot formation, which may help maintain arterial patency and reduce the risk of atherosclerosis. Some sulfated polysaccharides also appear to modulate lipid metabolism, potentially lowering cholesterol levels and thereby indirectly supporting arterial health.

While these findings are promising, most of the evidence remains preclinical, with limited human clinical trials. The mechanisms proposed include interference with coagulation pathways, inhibition of smooth muscle cell proliferation, and antioxidant activity, all of which are beneficial for arterial health. However, more research—especially large, well-controlled human studies—is needed to confirm these effects and establish safe, effective dosages. Thus, the use of sulfated polysaccharides for arterial support is scientifically plausible and supported by early evidence, but it is not yet strongly validated for clinical use.

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Products containing Sulfated polysaccharide

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