Evidence supporting the use of: Triterpene Saponin
For the body system: Arteries
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Triterpene saponins are a class of natural compounds found in various plants, including well-known medicinal herbs such as ginseng (Panax ginseng), licorice (Glycyrrhiza glabra), and horse chestnut (Aesculus hippocastanum). Traditionally, extracts containing triterpene saponins have been used in herbal medicine systems to promote cardiovascular health, which includes support for arterial function. For example, horse chestnut seed extract, rich in the saponin aescin, has been used for conditions related to venous insufficiency and, more broadly, to support vascular health in European herbal traditions. Scientific studies on triterpene saponins suggest potential vascular benefits, such as anti-inflammatory properties, reduction of vascular permeability, and mild vasoprotective effects. However, most of the evidence is preliminary, derived from animal models or in vitro studies rather than large-scale human clinical trials specifically targeting arteries. Some clinical trials of horse chestnut extract show benefits in venous disorders, but evidence for direct arterial support is limited. In summary, the use of triterpene saponins for arterial health is mostly rooted in traditional herbal practices, with some emerging but not definitive scientific support. The evidence specifically linking triterpene saponins to arterial support in humans is modest, justifying a rating of 2 on the evidence scale.
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arjun tree
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beet
bergamot
bilberry
black cumin
black currant
black garlic
sesame
black tea
blackberry
blueberry
bonito peptide
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broccoli
brussel sprouts
butcher's broom
calamari oil
campesterol
canola oil
capsaicinoids
catechins
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cherry
chia seed
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citrus bioflavonoids
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citrus sinensis (proprietary)
coenzyme Q10 (CoQ10)
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fish oil
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ginkgo biloba
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hesperetin
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horse chestnut
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