Evidence supporting the use of: Vitamin E (alpha tocotrienol)
For the body system: Arteries
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Alpha-tocotrienol is one of the eight forms of vitamin E, which includes both tocopherols and tocotrienols. While the most researched form is alpha-tocopherol, emerging evidence suggests that tocotrienols, including alpha-tocotrienol, may have unique benefits for arterial and cardiovascular health. Several in vitro and animal studies have demonstrated that tocotrienols possess stronger antioxidant properties compared to tocopherols. These antioxidants help protect the arterial walls from oxidative stress and lipid peroxidation, processes that are central to the development of atherosclerosis.
Some human studies, though limited, indicate that tocotrienol supplementation may help lower cholesterol levels and reduce arterial stiffness, both of which are beneficial for arterial health. For example, randomized controlled trials have shown that tocotrienol-rich fractions can lower LDL cholesterol and markers of inflammation in subjects with hypercholesterolemia, though these effects are not as robust or consistent as those seen with some pharmaceutical interventions. Additionally, tocotrienols may inhibit the progression of arterial plaque by suppressing the activity of HMG-CoA reductase, an enzyme involved in cholesterol synthesis.
Despite these promising findings, the body of clinical evidence is still relatively small and more research, especially large-scale human trials, is needed to confirm these effects. Thus, while there is scientific support for the use of alpha-tocotrienol in supporting arterial health, the evidence is considered moderate at this time.
More about Vitamin E (alpha tocotrienol)
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ajoenealgal oil
alpha-linolenic acid (ALA)
amino acids
anchovies
anthocyanins
apple
arjun tree
artichoke
astaxanthin
barley
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bergamot
bilberry
black cumin
black currant
black garlic
sesame
black tea
blackberry
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bonito peptide
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broccoli
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coenzyme Q10 (CoQ10)
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rose hips
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sardines
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vitamin B
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terpene lactones
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trace minerals
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algae
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Other body systems supported by Vitamin E (alpha tocotrienol)
ArteriesBlood
Brain
Capillaries
Circulatory System
Heart
Immune System
Lungs
Mitochondria
Nerves
Reproductive System
Skin