Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Blueberry (Vaccinium spp.) is often promoted for cardiovascular health, including the prevention or management of arteriosclerosis (hardening of the arteries). The scientific justification for this use is primarily based on the high content of polyphenols, especially anthocyanins, found in blueberries. These compounds have demonstrated antioxidant, anti-inflammatory, and vasoprotective effects in preclinical studies. Several animal studies and a limited number of small human trials suggest that regular blueberry consumption may improve markers of vascular function, decrease oxidative stress, and reduce blood pressure—all factors associated with the development of arteriosclerosis.

However, direct evidence specifically linking blueberry consumption to the prevention or reversal of arteriosclerosis in humans is limited. Most clinical studies focus on surrogate endpoints such as endothelial function, arterial stiffness, or lipid profiles, rather than hard clinical outcomes or direct imaging of arterial plaque. Reviews and meta-analyses generally conclude that there is promising but preliminary evidence for cardiovascular benefits, and that larger, well-controlled trials are needed.

In summary, blueberries have a plausible scientific rationale and some supporting human data for cardiovascular benefits relevant to arteriosclerosis, but robust clinical evidence is lacking. Therefore, the overall evidence supporting their use specifically for arteriosclerosis rates as modest (2 out of 5).

More about blueberry
More about Arteriosclerosis

Other ingredients used for Arteriosclerosis

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