Evidence supporting the use of: Flavanols
For the health condition: Arteriosclerosis
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Flavanols, a subgroup of flavonoids found in foods such as cocoa, tea, apples, and berries, have been the subject of numerous studies investigating their cardiovascular benefits, including potential effects on arteriosclerosis (the thickening and hardening of arterial walls). Scientific evidence suggests that flavanols may improve endothelial function, decrease oxidative stress, and reduce inflammation—all factors implicated in the development and progression of arteriosclerosis. Clinical trials, particularly those involving cocoa flavanols, have demonstrated improvements in flow-mediated dilation, a measure of vascular endothelial health. Some epidemiological studies also correlate higher dietary intake of flavanol-rich foods with reduced risk of cardiovascular events. However, while these findings are promising, most of the evidence is derived from short-term studies with surrogate endpoints (such as blood vessel function markers) rather than long-term outcomes like reduction in arterial plaque or clinical cardiovascular events. Meta-analyses suggest a modest but consistent benefit in vascular health, but direct evidence for flavanols preventing or treating established arteriosclerosis in humans is limited. The current scientific consensus supports a beneficial role for flavanols in cardiovascular health, but more research—especially long-term, large-scale clinical trials—is needed to firmly establish their efficacy in the prevention or treatment of arteriosclerosis specifically.
Other ingredients used for Arteriosclerosis
AjoeneAlcohol
Allicin
Alliin
alpha-linolenic acid (ALA)
AMP-activated protein kinase (AMPK)
anchovies
anthocyanidins
anthocyanins
anthocyanosides
apple
Aronia melanocarpa
beet
berberine
bilberry
black garlic
black tea
blueberry
catechins
chocolate
chokeberry
cocoa
coenzyme Q10 (CoQ10)
curcumin
d-alpha tocopherol
danshen
EPA (eicosapentaenoic acid)
epicatechin
fiber
fiber blend (proprietary)
fish oil
flavanols
flavans
flavonoids
flavonols
garlic
garlic bulb
ginkgo biloba
ginseng
grape
green tea
hawthorn
hesperetin
hesperidin
hydroxytyrosol
inositol nicotinate
jiaogulan
Lactotripeptides
Legume protein
Ligustrazin
magnesium
Marine lipid
Monacolin
Monounsaturated fat
Naringin
Nattokinase
Niacin (vitamin B3)
Oleuropein
Oligomeric proanthocyanidins
olive
omega-3 fatty acids
onion
Phthalides
Pistachio
policosanol
Polydatin
polyphenols
polyunsaturated fat
proanthocyanidins
Propionyl-L-Carnitine
psyllium
Puerarin
quercetin
red yeast rice
resveratrol
rutin
S-allylcysteine
Salvianolic acid
Sesamin
sitostanol
soy isoflavones
soybean
Taxifolin
tocotrienols
turmeric
Tyrosol
vitamin C
vitamin D
vitamin E
Walnut
Xantinol Nicotinate
Other health conditions supported by flavanols
Alzheimer's DiseaseArteriosclerosis
Cancer (natural therapy for)
Cancer (prevention)
Cardiovascular Disease
Cholesterol (high)
Circulation (poor)
Circulation (to the brain)
Congestive Heart Failure
Dementia
Diabetes
Diabetic Retinopathy
Hypertension
Inflammation
Macular Degeneration
Memory and Brain Function
Metabolic Syndrome
Osteoporosis
Peripheral Neuropathy
Rheumatoid Arthritis
Strokes
Triglycerides (high)
Varicose Veins
Wrinkles
