Relationship: Arteriosclerosis and grape

Evidence supporting the use of: Grape
For the health condition: Arteriosclerosis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Grapes, particularly their skins and seeds, are rich in polyphenols such as resveratrol, flavonoids, and proanthocyanidins, which have been researched for their cardiovascular benefits, including potential roles in the prevention and management of arteriosclerosis (the thickening and hardening of arterial walls). Several clinical and epidemiological studies have demonstrated that regular consumption of grape products, especially red wine and grape seed extracts, is associated with improved endothelial function, reduced oxidative stress, and decreased inflammation—all factors implicated in arteriosclerosis development. For instance, resveratrol has been shown in laboratory and some human studies to inhibit LDL oxidation, suppress vascular smooth muscle cell proliferation, and reduce platelet aggregation, all of which contribute to atherogenesis.

However, while the mechanistic data and some small clinical trials are promising, large-scale, long-term randomized controlled trials specifically evaluating grape-derived products for the prevention or treatment of arteriosclerosis are lacking. Major health organizations recognize the cardiovascular benefits of diets rich in fruits (including grapes), but do not specifically recommend grape supplements for arteriosclerosis due to insufficient direct evidence. Thus, the use of grape is scientifically plausible and somewhat supported by preliminary evidence, but not yet established as a primary or stand-alone treatment. Its consumption as part of a balanced diet is currently the best-supported approach.

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Other ingredients used for Arteriosclerosis

Ajoene
alpha-linolenic acid (ALA)
anchovies
anthocyanins
apple
beet
berberine
bilberry
black garlic
black tea
blueberry
canola oil
catechins
chokeberry
coenzyme Q10 (CoQ10)
turmeric
curcumin
d-alpha tocopherol
EPA (eicosapentaenoic acid)
fiber blend (proprietary)
fish oil
flavonols
garlic bulb
ginkgo biloba
ginseng
grape
onion
green tea
hawthorn
hesperetin
hesperidin
magnesium
Marine lipid
Naringin
Nattokinase
Niacin (vitamin B3)
olive
omega-3 fatty acids
policosanol
psyllium
quercetin
red yeast rice
resveratrol
rutin
sitostanol
soybean
tocotrienols
vitamin C
vitamin D
vitamin E
jiaogulan
polyphenols
cocoa
AMP-activated protein kinase (AMPK)
soy isoflavones
Alcohol
Aronia melanocarpa
Allicin
anthocyanidins
Alliin
anthocyanosides
chocolate
danshen
epicatechin
fiber
flavonoids
flavans
flavanols
garlic
hydroxytyrosol
inositol nicotinate
Legume protein
Ligustrazin
Lactotripeptides
Monacolin
Monounsaturated fat
Oleuropein
Oligomeric proanthocyanidins
Puerarin
Polydatin
proanthocyanidins
Propionyl-L-Carnitine
polyunsaturated fat
Phthalides
Pistachio
Salvianolic acid
S-allylcysteine
Sesamin
Tyrosol
Taxifolin
Walnut
Xantinol Nicotinate

Products containing grape

Health Concerns

Brands

Evidence supporting the use of: Grape
For the health condition: Arteriosclerosis

Table of Contents

Synopsis

Other ingredients used for Arteriosclerosis

Other health conditions supported by grape

Products containing grape

Health Concerns

Brands

Evidence supporting the use of: GrapeFor the health condition: Arteriosclerosis

Table of Contents

Synopsis

Other ingredients used for Arteriosclerosis

Other health conditions supported by grape

Products containing grape

Evidence supporting the use of: Grape
For the health condition: Arteriosclerosis