Evidence supporting the use of: Hydroxytyrosol
For the health condition: Arteriosclerosis
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Hydroxytyrosol and Arteriosclerosis: Evidence Overview
Hydroxytyrosol, a phenolic compound found in olives and olive oil, has attracted scientific interest for its potential cardiovascular benefits, including effects on arteriosclerosis (hardening and narrowing of the arteries). Preclinical studies demonstrate that hydroxytyrosol exhibits strong antioxidant and anti-inflammatory properties. These mechanisms are relevant because oxidative stress and inflammation significantly contribute to the development of arteriosclerosis.
Animal studies and in vitro experiments have shown that hydroxytyrosol can reduce the oxidation of low-density lipoprotein (LDL) cholesterol, inhibit endothelial dysfunction, and decrease markers of vascular inflammation, all of which are implicated in arteriosclerosis. Some early human studies and clinical trials involving olive oil polyphenols (hydroxytyrosol being a primary component) suggest improved endothelial function and reduced oxidative stress, factors that may help slow arteriosclerotic processes.
However, direct clinical evidence specifically linking isolated hydroxytyrosol supplementation to the prevention or treatment of arteriosclerosis in humans remains limited. Most human data come from broader studies on olive oil consumption rather than hydroxytyrosol alone. Thus, while mechanistic and indirect human evidence is promising, more robust clinical trials are needed to confirm its efficacy for arteriosclerosis specifically.
Other ingredients used for Arteriosclerosis
Ajoenealpha-linolenic acid (ALA)
anchovies
anthocyanins
apple
beet
berberine
bilberry
black garlic
black tea
blueberry
canola oil
catechins
chokeberry
coenzyme Q10 (CoQ10)
turmeric
curcumin
d-alpha tocopherol
EPA (eicosapentaenoic acid)
fiber blend (proprietary)
fish oil
flavonols
garlic bulb
ginkgo biloba
ginseng
grape
onion
green tea
hawthorn
hesperetin
hesperidin
magnesium
marine lipid
naringin
nattokinase
niacin (vitamin B3)
olive
omega-3 fatty acids
policosanol
psyllium
quercetin
red yeast rice
resveratrol
rutin
sitostanol
soybean
tocotrienols
vitamin C
vitamin D
vitamin E
jiaogulan
polyphenols
cocoa
AMP-activated protein kinase (AMPK)
soy isoflavones
Alcohol
Aronia melanocarpa
Allicin
anthocyanidins
Alliin
anthocyanosides
Chocolate
Danshen
epicatechin
Fiber
Flavonoids
Flavans
Flavanols
Garlic
Hydroxytyrosol
Inositol nicotinate
Legume protein
Ligustrazin
Lactotripeptides
Monacolin
Monounsaturated Fat
Oleuropein
Oligomeric proanthocyanidins
Puerarin
Polydatin
Proanthocyanidins
Propionyl-L-Carnitine
Polyunsaturated Fat
Phthalides
Pistachio
Salvianolic acid
S-allylcysteine
Sesamin
Tyrosol
Taxifolin
walnut
Xantinol Nicotinate
Other health conditions supported by Hydroxytyrosol
Alzheimer's DiseaseArteriosclerosis
Arthritis
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cardiovascular Disease
Cholesterol (high)
Circulation (poor)
Diabetes
Fatty Liver Disease
Free Radical Damage
Hypertension
Inflammation
Memory and Brain Function
Metabolic Syndrome
Rheumatoid Arthritis
Triglycerides (high)
Wrinkles