Evidence supporting the use of: Oleuropein
For the health condition: Arteriosclerosis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Oleuropein, a phenolic compound found predominantly in olive leaves and olive oil, has garnered scientific interest for its potential cardiovascular benefits, including its effects on arteriosclerosis (the thickening and hardening of arterial walls). Preclinical studies suggest that oleuropein exhibits antioxidant, anti-inflammatory, and lipid-lowering properties. For example, animal studies have shown that oleuropein supplementation can reduce oxidative stress markers and inhibit the formation of atherosclerotic lesions by decreasing low-density lipoprotein (LDL) oxidation and modifying lipid profiles. In vitro research has also demonstrated that oleuropein can inhibit the expression of adhesion molecules and cytokines involved in the development of arterial plaques. However, human clinical evidence remains limited. A few small studies have indicated that olive leaf extracts, which contain oleuropein, may help reduce blood pressure and improve lipid profiles, both of which are risk factors for arteriosclerosis. But direct evidence of oleuropein's effects on established arteriosclerosis in humans is lacking. Thus, while there is a scientific rationale for its use and some supportive early evidence, more robust clinical trials are needed to confirm oleuropein’s effectiveness in treating or preventing arteriosclerosis in humans.

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Products containing Oleuropein

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