Evidence supporting the use of: Pistachio
For the health condition: Arteriosclerosis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Pistachios (Pistacia vera) have been studied for their potential cardiovascular benefits, including their impact on arteriosclerosis (the thickening and hardening of arterial walls). The scientific evidence supporting their use for arteriosclerosis is modest but present. Several clinical trials and epidemiological studies suggest that regular consumption of pistachios can favorably modify cardiovascular risk factors. Pistachios are rich in mono- and polyunsaturated fatty acids, fiber, antioxidants (such as lutein and γ-tocopherol), and plant sterols. These components are associated with improved lipid profiles, reduced LDL cholesterol, and increased HDL cholesterol—all relevant for arteriosclerosis risk reduction. For example, a randomized controlled trial published in the American Journal of Clinical Nutrition (2010) found that diets including pistachios reduced total cholesterol and LDL cholesterol in adults with elevated blood lipids. Additionally, a few studies suggest improvements in endothelial function and decreased markers of oxidative stress when pistachios are included as part of a heart-healthy diet.

However, direct evidence showing that pistachio consumption prevents or reverses arteriosclerosis (as measured by arterial thickness or plaque burden) is lacking. Most research to date focuses on surrogate markers rather than clinical endpoints or imaging-based outcomes. Therefore, while there is some scientific basis for recommending pistachios as part of an overall strategy to reduce arteriosclerosis risk, the strength of the evidence is moderate and primarily indirect.

More about Pistachio
More about Arteriosclerosis

Products containing Pistachio

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