Evidence supporting the use of: Vitamin E (tocotrienol unspecified)
For the health condition: Arteriosclerosis

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin E, including tocotrienols, has been investigated for its potential role in the prevention and management of arteriosclerosis due to its antioxidant properties. Arteriosclerosis involves the hardening and narrowing of arteries, often linked to oxidative stress and inflammation, which can damage vascular endothelium and promote the development of atherosclerotic plaques. Tocotrienols, a subgroup of Vitamin E, have shown in preclinical studies to inhibit cholesterol synthesis, reduce inflammation, and limit oxidative damage to blood vessels. Some small clinical trials and animal studies suggest tocotrienols may improve lipid profiles and reduce arterial plaque formation. For example, a handful of controlled studies have reported modest improvements in cholesterol levels and markers of arterial health in subjects supplemented with tocotrienols. However, the majority of large-scale human trials examining Vitamin E (mostly alpha-tocopherol, not tocotrienols) have not consistently demonstrated a significant reduction in cardiovascular events or clear regression of arteriosclerosis. The evidence specifically for tocotrienols is still limited and primarily preliminary, lacking robust, long-term randomized controlled trials in humans. As such, while there is a scientific rationale and early evidence for using Vitamin E/tocotrienols against arteriosclerosis, the overall level of scientific validation remains low to moderate, and major clinical guidelines do not recommend Vitamin E supplementation specifically for arteriosclerosis prevention or treatment at this time.

More about Vitamin E (tocotrienol unspecified)
More about Arteriosclerosis

Products containing Vitamin E (tocotrienol unspecified)

We currently have no products on Vitabase that contain this ingredient.