Relationship: Arthritis and vitamin C

Evidence supporting the use of: Vitamin C
For the health condition: Arthritis

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Synopsis
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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin C (ascorbic acid) is an essential nutrient with antioxidant properties, and its potential role in arthritis—particularly osteoarthritis (OA) and rheumatoid arthritis (RA)—has been explored in scientific research. Vitamin C is involved in collagen synthesis, which is significant because cartilage, a key tissue damaged in arthritis, is rich in collagen. Some epidemiological studies suggest that higher dietary vitamin C intake is associated with a reduced risk of developing certain types of arthritis, particularly OA. For example, a prospective cohort study found that individuals with higher vitamin C intake had a lower risk of developing knee OA.

However, randomized controlled trials specifically investigating vitamin C supplementation for arthritis treatment are limited and have produced mixed results. While vitamin C’s antioxidant properties may theoretically help reduce oxidative damage and inflammation in joint tissues, clinical improvements in arthritis symptoms or progression have not been strongly or consistently demonstrated.

There is also some evidence that excessive vitamin C supplementation may be harmful, as high doses have been linked with increased risk of kidney stones and, paradoxically, may exacerbate some inflammatory pathways in certain conditions. Current guidelines do not recommend vitamin C supplementation specifically for arthritis, but maintaining adequate intake as part of a balanced diet is encouraged for general health and collagen maintenance.

In summary, while there is a plausible scientific rationale and some supportive observational evidence, strong clinical evidence for vitamin C supplementation as a treatment for arthritis is lacking.

More about vitamin C
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Other ingredients used for Arthritis

3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
Abalone
Abies spectabilis
Abrus
Abuta
Acacetin
Achyranthes
Aconite
Actaea spicata
adrenal cortex
Ajuga
Akebia
Alantolactone
Albizia
Alfalfa
Algae
algal oil
Allicin
Allium tuberosum
Allspice
Aloe vera
alpha-humulene
alpha-linolenic acid (ALA)
alpha-lipoic acid
alpha-pinene
alpinia galangal
amber
American Liverleaf
amino acids
aminomonosaccharide
Amor seco
AMP-activated protein kinase (AMPK)
ampelopsin
anamu
Andrographis
andrographolide
Anemone
Angelica
animal Tissue
Anserina
anthocyanidins
anthocyanins
antler
apigenin
apocynin
apple cider vinegar
Aralia
Arani
Ardisia
Arisaema
arjunic acid
Ascophyllum nodosum
ash
ashwagandha
aspen
astaxanthin
Asteraceae
astragalin
astragaloside
atractylone
aucubin
avenacosides
avens
avocado
babassu
bacteria
baicalein
baicalin
Baikal Skullcap
balsam
bamboo
banyan
barbary matrimony vine
barbasco
barberry
Barleria
barrenwort
Basidiomycota
basil
Bassia scoparia
bayleaf
bee hive
bee pollen
bee products
bee propolis
bee venom
benzyl isothiocyanate
Bergenia
bergenin
bermuda grass
berry
beta caryophyllene
beta-glucan
betony
Bidens pilosa
big quaking grass
bioflavonoids
biota seed
birch
bishop\'s weed
bittersweet
black cumin
black currant
black galingale
black garlic
black ginger
black nightshade
black pepper
black poplar
black root
black seed
black tea
Black willow
blackberry
blackboard tree
Blepharis
blubber oil
blueberry
Boerhavia diffusa
bogbean
Bombax
bone marrow
bone protein
borage
borage oil
Borassus aethiopum
borassus palm
borneol
boron
Boswellia
Boswellic Acid
bovine
bovine cartilage / glycosaminoglycan
bovine protein
boxwood
broccoli
bromelain
Broussonetia
buckthorn
bugbane
Bulnesia sarmientoi
Bupleurum
bur-reed
burdock
burning bush
Butea monosperma
C-phycocyanin
cabbage
cactus
Caesalpinia crista
calamari oil
Calanus finmarchicus
camelina oil
Camellia sinensis
cannabichromene
cannabidiol
cannabigerol
Cannabis sativa oil
capillary artemisia
capsaicin
capsaicinoids
capsicum
carrot
Carthamus
cartilage
caryophyllene
cat's claw
caterpillar mushroom
cayenne pepper
cedar
Celastrus
celery
Centella asiatica
Centella triterpenes
Cetylated Fatty Acids
cherry
Chinese fleeceflower
Chinese mountain ant
Chinese pond turtle
Chinese raisintree
Chinese silkvine
Chlorophytum
chondroitin
chrysanthemum
chuchuhuasi
chymotrypsin
cinnamaldehyde
Cinnamomum
cinnamon
Citrus
clematis
Clerodendrum indicum
Clerodendrum indicum
Clerodendrum phlomidis
Clerodendrum trichotomum
clove
Cnidium
cod liver oil
collagen
collard
commiphora
conjugated linoleic acid (CLA)
copaiba oil
copper
Corallina officinalis
cordyceps
corktree
cortisol
cowage seed
cowherb
Crinum latifolium
cruciferous
cryptoxanthin
Curcuma
curcumen
curcumin
Curcuminoid
currant
curry leaf
cyanidin
cytokines
daphne
devil's claw
devil\'s club
DHA (docosahexaenoic acid)
Dihomo-gamma-linolenic acid
Dimethyl sulfoxide (DMSO)
Dimorphandra mollis
dioscorea
Dipsacus
diterpenes
docosahexaenoic Acid
dodder
dodeca-2E, 4E-dienoic acid isobutylamide
DPA (docosapentaenoic acid)
dulse
Dwarf Nettle
Echium
Ecklonia
Eclipta
eicosapentaenoic acid
elephant\'s head
elk antler
emblicanin
emu oil
enzyme blend
enzymes blend (proprietary)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
Erodium cicutarium
Erythropalum scandens
essential oil blend
eugenol
Eupolyphaga sinensis
European Elder
European five-finger grass
evening primrose oil
evening primrose oil
Evodia
fang-feng
fat liver oil
fatty acids
ferulic acid
Ficus religiosa
Ficus simplicissima
fish
fish oil
fish protein
flavones
flavonoids
flavonols
flavonones
flaxseed
Flemingia philippinensis
Flueggea suffruticosa
fo-ti
frankincense
fructoborate
fruit
fucoidan
fulvic acid
fungus
Galbanum
gamma linolenic acid (GLA)
gamma tocopherol
ganoderma
gastrodia
genipap
genistein
Gentiana macrophylla
geranium
Gigartina
ginger
ginseng
Ginsenosides
Glechoma hederacea
glucosamine
Glycosaminoglycans
Gnaphalium
goji berry
golden eye-grass
golden ragwort
Golden Willow
gooseberry
gotu kola
green tea
green-lipped mussel
guelder rose
guggul
Guggulsterones
Gumweed
Gypenoside
Haematococcus pluvialis
haliotis
Harpagoside
heal-all
heartwood
Helicteres isora
Hellebore
Hemidesmus
hemp
hemp oil
Hempnettle
Herb Robert
herbal blend (proprietary)
honey
horny goat weed
horsetail
Huang hua
Humulones
hyaluronic acid
hydroxytyrosol
Hyperoside
Ilex
Indian coraltree
Indian fagonia
Indian frankincense
Indian kinotree
Indian nightshade
Indian sarsparilla
Indian tinospora
indigo leaves
iridoid glycosides
iridoids
isoliquiritigenin
isoquinoline alkaloids
Japanese kadsura
Jatoba
Jatropha macrantha
jiaogulan
juglans cinerea
juniper berries
Kachnar
Kaempferol
kale
knotweed
Kokilaksha
krill oil
kudzu
Labdanum
labrador tea
Lebbek
Ledebouriella
lemongrass
Lesser speargrass
lichen
Ligusticum
ligustilides
Ligustrazin
linalool
Lindera
lingzhi
linseed oil
Lithothamnion
Litsea
Lophira lanceolata
Loranthus
lotus
luffa
luteolin
Lycium
Maclura tricuspidata
madder
magnesium
magnolol
Malay bush
Manchurian thorn
mangiferin
mangostin
Marine fat
Marine lipid
Marine protein
Maslinic acid
Matapalo Tree
Meadowsweet
Melia
Menthol oil
Mesua
Methylsulfonylmethane (MSM)
Mezoneuron benthamianum
Microbial enzymes (proprietary)
Microcrystalline hydroxyapatite concentrate (MCHC)
Microtea debilis
Millet
Millettia
Monoterpenes
Morinda
Moringa
Morus
Mucopolysaccharide
Mugwort
Mulberry
Mustard
mustard seed
Myrcene
Myricitrin
Myristoleate
Myrrh
N-acetyl-cysteine (NAC)
N-acetyl-glucosamine
Naringenin
Nettle
Niacinamide (vitamin B3)
Nigella seed
Night jessamine
Nimbidin
Nobiletin
noni
Nutmeg
Nymphaea nouchali
Ocotillo
Oldenlandia diffusa
oleanolic acid
oleic acid
Oleoperin
Oligomeric proanthocyanidins
olive
omega-3 fatty acids
orange
oregon grape
Oroxylum indicum
Osthole
paeoniflorin
Palmitoylethanolamide (PEA)
Pansit-pansitan
papain
papaya
Pata de Vaca
Patrinia
Pentacyclic triterpenoids
Pentatropis capensis
peony
Pepper
Peptides
Persimmon
Petiveria
Phaeophyceae
Phellodendron
phellodendron amurense
phenolic compounds
Phenylpropanoids
phlorotannins
phospholipids
Phyllanthus
Physalis angulata
phytocannabinoids
pine bark
pineapple
Piper chaba
Piper nigrum
Piperine
Plankton
plantain
Pluchea
Plumbago zeylanica
Pokeweed
pollen
Polydatin
Polygonum
polymethoxylated flavones
polyphenols
Polypodium
polyunsaturated fat
pomegranate
poplar
Portulaca
pregnenolone
Premna
prepared aconite tuber
procyanidin
proteoglycans
proteolytic enzymes
Prunus
Psacalium peltatum
pumpkin
punarnava
purslane
Pycnogenol
Pyrola
Qin Jiao
Queen's Delight
quercetin
raspberry
reishi mushroom
resveratrol
rhizome
Rhododendron
rockweed
Rooibos
root tuber
Rosa roxburghii
rose hips
rosemary
rosmarinic acid
royal jelly
Rubia cordifolia
Rubiaceae
Rubus
rue
Ruscogenins
Ruscus
Safed musli
Sagebrush
Salmon Oil
Salvia
Salvianolic acid
Sambucus nigra
Sandalwood
Sandy Everlasting
saponins
sarsaparilla
Schizochytrium
schizonepeta
Scoparia dulcis
Scopoletin
scrophularia root
seaweed
Self-Heal
Semecarpus anacardium
Sensitive Plant
Serrapeptase
serratiopeptidase
sesame
Sesamin
Sesbania
Sesquiterpenes
Sete sangrias
Shark Liver Oil
Shataverins
shen-chu
Shilajit
Shogaol
Sichuan Lovage
Sickle-leaf hare's ear
Sicklepod
Siegesbeckia
silk tree
Silkmoth
Sinapis arvensis
Sinomenium acutum
Skunkvine
Smartweed
Smilagenin
smilax
Snakeroot
Solanaceae
Solanum indicum
solomon's seal
Sophora
soursop
Southern Tsangshu
Spatholobus
specialized pro-resolving mediators (SPMs)
Sphaeranthus indicus
Spikenard
spinach
Spiraea
spirulina
spruce
squawvine
Stachytarpheta cayennensis
Stearidonic acid
Stellaria dichotoma
Stereospermum
Stilbenoid
strawberry
strontium
Sulfated polysaccharide
suma
Sumac
Sweet Bay
sweetgums
Sword Bean
Szechuan lovage
Tagetes
Tamarind
Tanshinone
Taraxacin
Taraxasterol
Taraxol
Taxillus chinensis
Taxillus sutchuenensis
Tea
Terminalia
Terpenoids
thyme
Thymoquinone
Tillandsia
Tinospora cordifolia
Toadflax
trace minerals
Tree of heaven
Tremella
Triphala
Triterpenes
Troxerutin
Tulbaghia
Tumerone
turmeric
typhonium
ubiquinol
Uncaria
Ursolic Acid
Verbascoside
Veronica
Vine tea
Viola
Violet
vitamin B
vitamin B6
vitamin C
vitamin D
vitamin D3
vitamin E
Vitexicarpin
Vitexin
Walnut
Water Pepper
Watercress
wheat grass
White Poplar
white willow
Wild yam
Willow
Willow Bracket
Wintergreen
Withanolides
Wrightia tinctoria
Wulinshen
xanthium (cockleburs)
Xanthone
Xanthophyll
Yellow root
Yellow-Fruit Nightshade
Yerba buena
Yucca
Yuzu
zanthoxylum
Zinc
Zingerone
Zingibain
Zingiberene
Zucchini

Other health conditions supported by vitamin C

Abrasions
Abscesses
Acne
Acquired Immune Deficiency Syndrome
Addictions (general remedies for)
Addison's Disease
Adrenal Fatigue
Age Spots
Aging (prevention)
Alcoholism
Allergies (food)
Allergies (respiratory)
Alzheimer's Disease
Anal Fistula or Fissure
Anemia
Antibiotics (alternatives to)
Antibiotics (side effects of)
Anxiety
Arteriosclerosis
Arthritis
Asthma
Athletic and Exercise Aids
Autism
Autoimmune Disorders
Bell's Palsy
Bites and Stings
Bladder Infection
Bleeding (external)
Bleeding (internal)
Blood Poisoning
Boils
Bronchitis
Bruises (healing)
Bruises (prevention)
Burns and Scalds
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Canker Sores
Capillary Weakness
Carbuncles
Cardiovascular Disease
Cartilage Damage
Cataracts
Cervical Dysplasia
Chemical Poisoning
Chemotherapy (reducing side effects)
Chicken Pox
Cholesterol (high)
Chronic Obstructive Pulmonary Disorder
Cold Sores
Colds (antiviral)
Colds (decongestant)
Colds (general)
Colds (prevention)
Colds (with fever)
Colon (atonic)
Congestion
Congestion (bronchial)
Congestion (lungs)
Congestion (sinus)
Conjunctivitis
Contagious Diseases
Convalescence
Copper Toxicity
Cough (dry)
Cough (general)
Cuts
Cystic Breast Disease
Cystic Fibrosis
Debility
Dementia
Denture Sores
Depression
Diabetes
Diabetic Retinopathy
Environmental Pollution
Epstein Barr Virus
Eye Problems
Eyesight (poor)
Fatigue
Fatty Liver Disease
Free Radical Damage
Gall Stones
Gastritis
Gingivitis
Glaucoma
Gonorrhea
Gout
Hair (loss or thinning)
Hair Care (general)
Heart (weakness)
Heavy Metal Poisoning
Hemorrhoids
Hepatitis
Herpes
Hot Flashes
Hypertension
Infection
Infection (bacterial)
Infection (viral)
Infertility
Inflammation
Inflammatory Bowel Disorders
Influenza
Injuries
Knees (weak)
Laryngitis
Lead Poisoning
Lesions
Leucorrhea
Leukemia
Ligaments (torn or injured)
Liver Detoxification
Lyme Disease
Macular Degeneration
Mastitis
Measles
Memory and Brain Function
Menorrhagia
Menstrual Irregularity
Menstruation (scant)
Metabolic Syndrome
Mononucleosis
Mumps
Nose Bleeds
Oral Surgery
Osteoporosis
Pancreatitis
PMS (general)
PMS Type C
PMS Type H
Pneumonia
Post Partum Weakness
Pregnancy (herbs and supplements for)
Progesterone (low)
Prolapsed Uterus
Prostatitis
Radiation Sickness
Rashes and Hives
Restless Leg Syndrome
Rheumatoid Arthritis
Rhinitis
Rhinitis, Allergic
Rosacea
Scars / Scar Tissue
Schizophrenia
Scratches and Abrasions
Scurvy
Shingles
Shock
Sinus Infection
Skin (infections)
Skin Care (general)
Sore Throat
Spider Veins
Spinal Disks
Sprains
Strep Throat
Stretch Marks
Sunburn
Surgery (healing from)
Surgery (preparation for)
Teeth (loose)
Tendonitis
Thrush
Tickle in Throat
Tonsillitis
Tooth Extraction
Toxemia
Triglycerides (high)
Tuberculosis
Ulcerations (external)
Ulcers
Uric Acid Retention
Urinary Tract Infections
Vaginitis
Varicose Veins
Warts
Wounds and Sores
Wrinkles

Products containing vitamin C

Health Concerns

Brands

Evidence supporting the use of: Vitamin C
For the health condition: Arthritis

Table of Contents

Synopsis

Other ingredients used for Arthritis

Other health conditions supported by vitamin C

Products containing vitamin C

Health Concerns

Brands

Evidence supporting the use of: Vitamin CFor the health condition: Arthritis

Table of Contents

Synopsis

Other ingredients used for Arthritis

Other health conditions supported by vitamin C

Products containing vitamin C

Evidence supporting the use of: Vitamin C
For the health condition: Arthritis