Evidence supporting the use of: 10-Undecenoic Acid
For the health condition: Athlete's Foot

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

10-Undecenoic acid, also known as undecylenic acid, is a naturally occurring fatty acid derived from castor oil. Its use in the treatment of athlete's foot (tinea pedis), a common fungal infection caused primarily by dermatophytes such as Trichophyton species, is scientifically supported. Undecylenic acid and its salts (especially zinc undecylenate) have demonstrated antifungal activity in vitro against dermatophytes. The mechanism of action is believed to involve disruption of the fungal cell membrane, inhibiting fungal growth and proliferation.

Over-the-counter antifungal products containing undecylenic acid have been available in the United States since the 1940s, and the U.S. Food and Drug Administration (FDA) recognizes undecylenic acid as a Category I antifungal agent for topical use against tinea pedis, along with clotrimazole and other azoles. Several clinical studies from the mid-20th century reported efficacy in treating athlete's foot, with cure rates comparable to other topical antifungals of that era. However, more recent large-scale, high-quality randomized controlled trials are limited, and newer antifungal agents may be more effective in some cases.

In summary, the use of 10-undecenoic acid for athlete's foot is justified by both historical precedent and moderate scientific evidence, particularly for mild cases. It remains an accepted and recognized topical antifungal treatment, though not the first-line therapy compared to some modern agents.

More about 10-Undecenoic Acid
More about Athlete's Foot

Other health conditions supported by 10-Undecenoic Acid

Athlete's Foot
Fungal Infections
Jock Itch
Skin (infections)
Thrush

Products containing 10-Undecenoic Acid

We currently have no products on Vitabase that contain this ingredient.