Evidence supporting the use of: Potassium caprylate
For the health condition: Athlete's Foot

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Potassium caprylate, the potassium salt of caprylic acid (octanoic acid), has demonstrated antifungal properties in vitro and is sometimes used in formulations targeting fungal skin infections, including Athlete’s Foot (tinea pedis). Scientific evidence supporting its use is limited but present. Caprylic acid and its salts disrupt fungal cell membranes, particularly those of Candida species and some dermatophytes, by integrating into lipid bilayers and causing leakage of cellular contents. Several laboratory studies have shown fungistatic and fungicidal effects of caprylic acid, but most data focus on Candida rather than the dermatophytes (Trichophyton, Epidermophyton) responsible for Athlete’s Foot.

Clinical studies specifically evaluating potassium caprylate for tinea pedis are sparse. Some over-the-counter topical products include fatty acid salts as part of multi-ingredient antifungal creams, but these are usually supported by anecdotal reports or extrapolation from in vitro findings. No major clinical trials have established potassium caprylate as a standalone or first-line therapy for Athlete’s Foot.

In summary, the scientific rationale for potassium caprylate’s antifungal activity exists, but direct clinical evidence for its efficacy in treating Athlete’s Foot is limited. It may be included in topical formulations as a supplementary antifungal agent, but it is not considered a primary or proven treatment based on current clinical standards.

More about Potassium caprylate
More about Athlete's Foot

Other health conditions supported by Potassium caprylate

Athlete's Foot
Fungal Infections
Thrush

Products containing Potassium caprylate

We currently have no products on Vitabase that contain this ingredient.