Evidence supporting the use of: Arginine
For the health condition: Athletic and Exercise Aids

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Arginine, an amino acid, is commonly marketed as an athletic and exercise aid due to its role as a precursor to nitric oxide (NO), which can promote vasodilation and potentially improve blood flow to muscles during exercise. This mechanism has led to the hypothesis that arginine supplementation might enhance exercise performance, increase oxygen delivery, and improve recovery. Several studies have investigated these claims, with mixed results. Some small clinical trials suggest that arginine supplementation may modestly improve exercise capacity, particularly in untrained or moderately trained individuals. However, larger and more rigorous studies in well-trained athletes generally show little to no performance benefit from arginine supplementation. Meta-analyses and systematic reviews conclude that evidence supporting arginine’s ergogenic effects is limited and inconsistent.

Arginine may have a more pronounced effect in populations with impaired endothelial function, rather than in healthy athletes. Its use as an exercise aid is therefore supported by a biological rationale and modest scientific evidence, but the overall clinical relevance and benefit for most athletes remain uncertain. Major sports and nutrition organizations do not currently recommend arginine as a performance-enhancing supplement. In summary, while arginine is scientifically investigated as an exercise aid, the level of supporting evidence is low to moderate.

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Other ingredients used for Athletic and Exercise Aids

7-Keto-DHEA
Acetyl L-carnitine
adenosine 5-triphosphate disodium (ATP)
Alpha D-ribofuranose
alpha-ketoglutarate (AKG)
amino acids
ashwagandha
astaxanthin
bacillus subtilis
beet
beta-alanine
black tea
bovine
branched-chain amino acids
caffeine
capsaicinoids
coenzyme Q10 (CoQ10)
collagen
colostrum
conjugated linoleic acid (CLA)
cordyceps
creatine monohydrate
curcumin
eleuthero
ginseng
green tea
guarana
guayusa
l-isoleucine
L-alanine
L-Alanyl-L-glutamine
L-arginine
l-carnitine
L-citrulline
L-glutamine
L-glycine
L-leucine
L-Ornithine
L-taurine
l-tyrosine
L-valine
maca
magnesium
maltodextrin
muira puama
Acetyl-L-Tyrosine
omega-3 fatty acids
ornithine alpha-ketoglutarate
Peppermint
protein
pyridoxal-5-phosphate (P-5-P)
rhodiola
black ginger
spirulina
tongkat ali
tribulus
vitamin C
watermelon
whey protein
suma
jiaogulan
capsicum
bee pollen
cistanche
electrolytes blend (proprietary)
yerba mate
Algae
cocoa
brown rice protein
sea salt
1,3,7-Trimethylpurine-2,6-dione
Arginine Alpha Ketoglutarate
Antler
Arginine Creatine
Arginine nitrate
Arachidonic Acid
Arginine malate
Arginine aspartate
Alpha glyceryl
Alpha-ketoisocaproic acid
Agmatine
Adenosine triphosphate (ATP)
Algal protein
Alpha hydroxyisocaproic acid
Arginine silicate
Bicarbonate
Beef Protein
Bovine Protein
Bulbine natalensis
Ba Ji Tian
BCAA
Camellia sinensis
Coconut
Casein
Cardarine
Capsinoids
Citrate malate
Capsiate
Creatine
D-Aspartic Acid
Dihydrocapsiate
Deer Velvet
D-Ribose
Ephedra
Eurycomanone
Elk antler
Eurycoma Longifolia
Ecdysteroids
Elthyl-Alpha-Guanido-Methyl-Ethanoate
Ecdysterone
Ephedrine
Fadogia agrestis
Guanidinoacetic acid
Ginsenosides
Glutamine
Growth factors
GMS-ribose
glucose
Glycocyamine
Guaranine
Glycerol
Higenamine
Hydroxymethylbutyrate
HMB Hydroxymethylbutyrate
Horny Goat Weed
Isomaltulose
Isoleucine
Kola Nut
Ketone Salts
Lactalbumin
Laxogenin
Macamides
Maral Root
Mineral ascorbate
Milk Protein
Methylxanthine
Methylliberine
Mate
Mushroom
Macaenes
Nitrous Malate (TM) Diarginine Malate
Ornithine
Phosphocreatine
Pyrroloquinoline Quinone
Paraxanthine
Phytoecdysteroid
Pyruvate
Phosphatidic Acid
Piper nigrum
Palatinose
Peptides
Quinoa Protein
Rhaponticum
Ribose
Robusta Coffee
Synephrine
Safed musli
salt
Sida cordifolia
Theobromine
Tripeptide
Trichilia catigua
Turkesterone
Trichopus zeylanicus
Theacrine
Teacrine
Tribulus Terrestris
Valine alpha-hydroxyisocaproate
Xanthine
yohimbine

Products containing Arginine

We currently have no products on Vitabase that contain this ingredient.