Arginine malate is a compound that combines the amino acid L-arginine with malic acid. Both components have been individually studied for their potential roles in supporting athletic performance. L-arginine serves as a precursor to nitric oxide, a molecule that dilates blood vessels and may increase blood flow to muscles during exercise, potentially enhancing oxygen and nutrient delivery. Malic acid is involved in the Krebs cycle, which is essential for energy production in cells.

Scientific evidence for the use of arginine malate as an athletic aid is limited and mixed. Some studies on L-arginine supplementation have shown modest improvements in exercise performance, endurance, and recovery, but results are inconsistent, with other trials showing no significant benefit. The addition of malate is theorized to further support energy metabolism, but direct studies on the arginine malate combination are sparse. A few small-scale studies suggest possible benefits in reducing muscle fatigue and improving aerobic performance, but the quality of evidence is low, with methodological limitations and small sample sizes.

Overall, while there is a plausible scientific rationale and some preliminary evidence, robust clinical trials are lacking. The current evidence base does not strongly support the use of arginine malate as an effective athletic or exercise aid, and its efficacy remains uncertain.