Evidence supporting the use of: Creatine
For the health condition: Athletic and Exercise Aids
Synopsis
Source of validity: Scientific
Rating (out of 5): 5
Creatine is one of the most extensively researched dietary supplements for athletic performance and exercise support. Numerous high-quality studies have demonstrated that creatine supplementation increases intramuscular phosphocreatine stores, which enhances the rapid regeneration of adenosine triphosphate (ATP) during high-intensity, short-duration activities such as sprinting, weightlifting, and other forms of explosive exercise. This biochemical effect translates into measurable improvements in muscle strength, power output, and lean muscle mass. Meta-analyses and systematic reviews consistently show that creatine monohydrate supplementation leads to significant gains in strength and performance in both trained athletes and recreational exercisers.
The safety profile of creatine is also well established, with long-term studies reporting no significant adverse health effects in healthy individuals when used at recommended dosages. The International Society of Sports Nutrition, among other organizations, recognizes creatine as both effective and safe for athletic and exercise-related purposes. While creatine is most effective for activities relying on the phosphagen energy system, some studies also report benefits for recovery and possibly cognitive function, though the evidence is strongest for improvements in physical performance. Overall, creatine is a scientifically validated supplement for supporting and enhancing athletic performance, particularly in sports and activities that require bursts of high-intensity effort.
Other ingredients used for Athletic and Exercise Aids
7-Keto-DHEAacetyl l-carnitine
adenosine 5-triphosphate disodium (ATP)
alpha d-ribofuranose
alpha-ketoglutarate (AKG)
amino acids
ashwagandha
astaxanthin
bacillus subtilis
beet
beta-alanine
black tea
bovine
branched-chain amino acids
caffeine
capsaicinoids
coenzyme Q10 (CoQ10)
collagen
colostrum
conjugated linoleic acid (CLA)
cordyceps
creatine monohydrate
curcumin
eleuthero
ginseng
green tea
guarana
guayusa
l-isoleucine
l-alanine
l-alanyl-l-glutamine
l-arginine
l-carnitine
l-citrulline
l-glutamine
l-glycine
l-leucine
l-ornithine
l-taurine
l-tyrosine
l-valine
maca
magnesium
maltodextrin
muira puama
Acetyl-L-Tyrosine
omega-3 fatty acids
ornithine alpha-ketoglutarate
peppermint oil
protein
pyridoxal-5-phosphate (P-5-P)
rhodiola
black ginger
spirulina
tongkat ali
tribulus
vitamin C
watermelon
whey protein
suma
jiaogulan
capsicum
bee pollen
cistanche
electrolytes blend (proprietary)
yerba mate
algae
cocoa
brown rice protein
sea salt
1,3,7-Trimethylpurine-2,6-dione
2, 17a-dimethyl-17b-hydroxy-5a-androst-2-ene
Arginine Alpha Ketoglutarate
Antler
Arginine Creatine
Arginine nitrate
Arachidonic Acid
Arginine malate
Arginine aspartate
Alpha glyceryl
Alpha-ketoisocaproic acid
Agmatine
adenosine triphosphate (ATP)
Algal protein
Alpha hydroxyisocaproic acid
Arginine silicate
Bicarbonate
Beef Protein
Bovine Protein
Bulbine natalensis
Ba Ji Tian
BCAA
Camellia sinensis
Coconut
Casein
Cardarine
Capsinoids
Citrate malate
Capsiate
Creatine
D-Aspartic Acid
Dihydrocapsiate
Deer Velvet
D-Ribose
Ephedra
Elk antler
Ecdysteroids
Elthyl-Alpha-Guanido-Methyl-Ethanoate
Ecdysterone
Ephedrine
glucose
Isoleucine
Ketone Salts
Milk Protein
Quinoa Protein
salt
yohimbine
Other health conditions supported by Creatine
Alzheimer's DiseaseAthletic and Exercise Aids
Depression
Diabetes
Fatigue
Inflammation
Memory and Brain Function
Migraine
Muscle Tone (lack of)
Muscular Dystrophy
Parkinson's Disease
Wasting