Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Creatine orotate is a form of creatine in which creatine is bound to orotic acid. Creatine itself is one of the most well-researched and widely used supplements for athletic performance and exercise support. Numerous high-quality studies have demonstrated that creatine monohydrate supplementation can increase muscle strength, power output, and lean mass, particularly during short-duration, high-intensity activities like weightlifting and sprinting. The mechanism involves increased phosphocreatine stores in muscle, which helps regenerate ATP, the primary energy molecule during intense exercise.

As for creatine orotate specifically, there is limited direct research comparing it to creatine monohydrate or evaluating its unique effects. The rationale for using the orotate form is that orotic acid may further support cellular energy production by acting as a precursor for pyrimidine synthesis and possibly enhancing creatine uptake or utilization, but this has not been definitively shown in clinical trials. Most available evidence and recommendations are extrapolated from studies on creatine monohydrate rather than creatine orotate itself.

In summary, while there is strong scientific validation for creatine (in general) as an athletic and exercise aid, the specific evidence for creatine orotate is less robust, though its use is based on the established benefits of creatine and theoretical advantages of the orotate component. More direct research is needed to determine if creatine orotate offers any distinct or superior benefits compared to other creatine forms.

More about Creatine Orotate
More about Athletic and Exercise Aids

Other ingredients used for Athletic and Exercise Aids

7-Keto-DHEA
acetyl l-carnitine
adenosine 5-triphosphate disodium (ATP)
alpha d-ribofuranose
alpha-ketoglutarate (AKG)
amino acids
ashwagandha
astaxanthin
bacillus subtilis
beet
beta-alanine
black tea
bovine
branched-chain amino acids
caffeine
capsaicinoids
coenzyme Q10 (CoQ10)
collagen
colostrum
conjugated linoleic acid (CLA)
cordyceps
creatine monohydrate
curcumin
eleuthero
ginseng
green tea
guarana
guayusa
l-isoleucine
l-alanine
l-alanyl-l-glutamine
l-arginine
l-carnitine
l-citrulline
l-glutamine
l-glycine
l-leucine
l-ornithine
l-taurine
l-tyrosine
l-valine
maca
magnesium
maltodextrin
muira puama
Acetyl-L-Tyrosine
omega-3 fatty acids
ornithine alpha-ketoglutarate
peppermint oil
protein
pyridoxal-5-phosphate (P-5-P)
rhodiola
black ginger
spirulina
tongkat ali
tribulus
vitamin C
watermelon
whey protein
suma
jiaogulan
capsicum
bee pollen
cistanche
electrolytes blend (proprietary)
yerba mate
algae
cocoa
brown rice protein
sea salt
1,3,7-Trimethylpurine-2,6-dione
2, 17a-dimethyl-17b-hydroxy-5a-androst-2-ene
Arginine Alpha Ketoglutarate
Antler
Arginine Creatine
Arginine nitrate
Arachidonic Acid
Arginine malate
Arginine aspartate
Alpha glyceryl
Alpha-ketoisocaproic acid
Agmatine
adenosine triphosphate (ATP)
Algal protein
Alpha hydroxyisocaproic acid
Arginine silicate
Bicarbonate
Beef Protein
Bovine Protein
Bulbine natalensis
Ba Ji Tian
BCAA
Camellia sinensis
Coconut
Casein
Cardarine
Capsinoids
Citrate malate
Capsiate
Creatine
D-Aspartic Acid
Dihydrocapsiate
Deer Velvet
D-Ribose
Ephedra
Elk antler
Ecdysteroids
Elthyl-Alpha-Guanido-Methyl-Ethanoate
Ecdysterone
Ephedrine
glucose
Isoleucine
Ketone Salts
Milk Protein
Quinoa Protein
salt
yohimbine

Other health conditions supported by Creatine Orotate

Athletic and Exercise Aids
Muscle Tone (lack of)

Products containing Creatine Orotate

We currently have no products on Vitabase that contain this ingredient.