Evidence supporting the use of: L-isoleucine
For the health condition: Athletic and Exercise Aids
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
L-isoleucine is one of the three branched-chain amino acids (BCAAs), along with leucine and valine, commonly used in sports and exercise supplements. Its inclusion in athletic and exercise aids is primarily based on its role in muscle metabolism and energy production during physical activity. Scientific studies have examined BCAAs, including isoleucine, for their potential to reduce muscle breakdown, decrease exercise-induced fatigue, and support muscle recovery. However, most of the research focuses on BCAAs as a group rather than on isoleucine alone.
Some evidence suggests that isoleucine may help regulate blood glucose and provide energy during endurance exercise, as it can be metabolized in skeletal muscle. However, the clinical significance of supplementing isoleucine alone for athletic performance or recovery is not strongly established. Systematic reviews and meta-analyses of BCAA supplementation show mixed results, with some indicating modest benefits for muscle soreness and recovery but limited impact on actual performance enhancement.
Overall, while isoleucine is scientifically recognized as an essential amino acid involved in muscle metabolism, the direct evidence supporting its isolated use as an athletic or exercise aid is limited. The available data justifies a rating of 2, reflecting weak but present scientific support, primarily for its inclusion as part of a BCAA blend rather than as a standalone supplement for athletic performance.
More about l-isoleucine
More about Athletic and Exercise Aids
Other ingredients used for Athletic and Exercise Aids
7-Keto-DHEAAcetyl L-carnitine
adenosine 5-triphosphate disodium (ATP)
Alpha D-ribofuranose
alpha-ketoglutarate (AKG)
amino acids
ashwagandha
astaxanthin
bacillus subtilis
beet
beta-alanine
black tea
bovine
branched-chain amino acids
caffeine
capsaicinoids
coenzyme Q10 (CoQ10)
collagen
colostrum
conjugated linoleic acid (CLA)
cordyceps
creatine monohydrate
curcumin
eleuthero
ginseng
green tea
guarana
guayusa
l-isoleucine
L-alanine
L-alanyl-L-glutamine
L-arginine
l-carnitine
L-citrulline
L-glutamine
L-glycine
L-leucine
L-ornithine
L-taurine
l-tyrosine
L-valine
maca
magnesium
maltodextrin
Muira puama
Acetyl-L-Tyrosine
omega-3 fatty acids
ornithine alpha-ketoglutarate
Peppermint
protein
pyridoxal-5-phosphate (P-5-P)
Rhodiola
black ginger
spirulina
Tongkat ali
tribulus
vitamin C
Watermelon
Whey protein
suma
jiaogulan
capsicum
bee pollen
cistanche
electrolytes blend (proprietary)
Yerba mate
Algae
cocoa
brown rice protein
sea salt
1,3,7-Trimethylpurine-2,6-dione
arginine alpha ketoglutarate
antler
arginine creatine
Arginine nitrate
arachidonic acid
Arginine malate
Arginine aspartate
Alpha glyceryl
Alpha-ketoisocaproic acid
Agmatine
Adenosine triphosphate (ATP)
Algal protein
Alpha hydroxyisocaproic acid
Arginine silicate
bicarbonate
Beef Protein
bovine protein
Bulbine natalensis
ba ji tian
BCAA
Camellia sinensis
coconut
casein
cardarine
capsinoids
citrate malate
capsiate
creatine
D-Aspartic Acid
dihydrocapsiate
deer velvet
D-Ribose
Ephedra
eurycomanone
elk antler
Eurycoma Longifolia
ecdysteroids
Ethyl-Alpha-Guanido-Methyl-Ethanoate
ecdysterone
ephedrine
Fadogia agrestis
guanidinoacetic acid
Ginsenosides
Glutamine
Growth factors
GMS-ribose
glucose
Glycocyamine
Guaranine
Glycerol
Higenamine
hydroxymethylbutyrate
HMB hydroxymethylbutyrate
horny goat weed
isomaltulose
Isoleucine
kola nut
ketone salts
lactalbumin
Laxogenin
macamides
maral root
Mineral ascorbate
Milk Protein
Methylxanthine
Methylliberine
Mate
Mushroom
macaenes
Nitrous Malate (TM) Diarginine Malate
Ornithine
Phosphocreatine
pyrroloquinoline quinone
paraxanthine
Phytoecdysteroid
pyruvate
Phosphatidic Acid
Piper nigrum
Palatinose
Peptides
Quinoa Protein
Rhaponticum
ribose
robusta coffee
Synephrine
Safed musli
salt
Sida cordifolia
Theobromine
Tripeptide
Trichilia catigua
Turkesterone
Trichopus zeylanicus
Theacrine
Teacrine
Tribulus Terrestris
Valine alpha-hydroxyisocaproate
Xanthine
Yohimbine
Other health conditions supported by l-isoleucine
Athletic and Exercise AidsBody Building
Muscle Tone (lack of)
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Klean Essential Aminos + HMB®
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Klean Isolate ™
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UltraInflamX Plus 360° Original Spice
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